Regulation of hematopoiesis by chemokine family members

被引:82
作者
Broxmeyer, HE
机构
[1] Indiana Univ, Sch Med, Walther Oncol Ctr, Indianapolis, IN 46202 USA
[2] Indiana Univ, Sch Med, Dept Microbiol & Immunol, Indianapolis, IN 46202 USA
[3] Walther Canc Inst, Indianapolis, IN USA
关键词
chemokines; stem/progenitor cells; proliferation; survival; migration/homing;
D O I
10.1007/BF02982544
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Chemokines, originally designated as chemoattractant cytokines, comprise a large family of molecules that have been implicated in a number of different functions mediated through chemokine receptors. Among these functions are regulatory roles in hematopoiesis that encompass effects on the proliferation, survival, and homing/migration of myeloid progenitor cells. This article reviews the field of chemokine regulation of hematopoiesis at the level of myeloid progenitor cells. (C) 2001 The Japanese Society of Hematology.
引用
收藏
页码:9 / 17
页数:9
相关论文
共 89 条
[41]   Impaired host defense, hematopoiesis, guanulomatous inflammation and type 1-type 2 cytokine balance in mice lacking CC chemokine receptor 1 [J].
Gao, JL ;
Wynn, TA ;
Chang, Y ;
Lee, EJ ;
Broxmeyer, HE ;
Cooper, S ;
Tiffany, HL ;
Westphal, H ;
KwonChung, J ;
Murphy, PM .
JOURNAL OF EXPERIMENTAL MEDICINE, 1997, 185 (11) :1959-1968
[42]   Oxidative stress and apoptosis in neurodegeneration [J].
Gorman, AM ;
McGowan, A ;
ONeill, C ;
Cotter, T .
JOURNAL OF THE NEUROLOGICAL SCIENCES, 1996, 139 :45-52
[43]   SDF-1 suppresses cytokine-induced adhesion of human haemopoietic progenitor cells to immobilized fibronectin [J].
Gotoh, A ;
Reid, S ;
Miyazawa, K ;
Broxmeyer, HE .
BRITISH JOURNAL OF HAEMATOLOGY, 1999, 106 (01) :171-174
[44]   IDENTIFICATION AND CHARACTERIZATION OF AN INHIBITOR OF HEMATOPOIETIC STEM-CELL PROLIFERATION [J].
GRAHAM, GJ ;
WRIGHT, EG ;
HEWICK, R ;
WOLPE, SD ;
WILKIE, NM ;
DONALDSON, D ;
LORIMORE, S ;
PRAGNELL, IB .
NATURE, 1990, 344 (6265) :442-444
[45]   The interaction between Cdc42 and WASP is required for SDF-1-induced T-lymphocyte chemotaxis [J].
Haddad, E ;
Zugaza, JL ;
Louache, F ;
Debili, N ;
Crouin, C ;
Schwarz, K ;
Fischer, A ;
Vainchenker, W ;
Bertoglio, J .
BLOOD, 2001, 97 (01) :33-38
[46]   Heptahelical receptor signaling: Beyond the G protein paradigm [J].
Hall, RA ;
Premont, RT ;
Lefkowitz, RJ .
JOURNAL OF CELL BIOLOGY, 1999, 145 (05) :927-932
[47]   The Exodus subfamily of CC chemokines inhibits the proliferation of chronic myelogenous leukemia progenitors [J].
Hromas, R ;
Cripe, L ;
Hangoc, G ;
Cooper, S ;
Broxmeyer, HE .
BLOOD, 2000, 95 (04) :1506-1508
[48]   BB-10010 - AN ACTIVE VARIANT OF HUMAN MACROPHAGE INFLAMMATORY PROTEIN-1-ALPHA WITH IMPROVED PHARMACEUTICAL PROPERTIES [J].
HUNTER, MG ;
BAWDEN, L ;
BROTHERTON, D ;
CRAIG, S ;
CRIBBES, S ;
CZAPLEWSKI, LG ;
DEXTER, TM ;
DRUMMOND, AH ;
GEARING, AH ;
HEYWORTH, CM ;
LORD, BI ;
MCCOURT, M ;
VARLEY, PG ;
WOOD, LM ;
EDWARDS, RM ;
LEWIS, PJ .
BLOOD, 1995, 86 (12) :4400-4408
[49]   Apoptosis [J].
Israels, LG ;
Israels, ED .
STEM CELLS, 1999, 17 (05) :306-313
[50]   SLC/Exodus2/6Ckine/TCA4 induces chemotaxis of hematopoietic progenitor cells: differential activity of ligands of CCR7, CXCR3, or CXCR4 in chemotaxis vs. suppression of progenitor proliferation [J].
Kim, CH ;
Broxmeyer, HE .
JOURNAL OF LEUKOCYTE BIOLOGY, 1999, 66 (03) :455-461