The renaissance of GSK3

被引:1333
作者
Cohen, P [1 ]
Frame, S
机构
[1] Univ Dundee, Sch Life Sci, MRC, Prot Phosphorylat Unit, Dundee DD1 5EH, Scotland
[2] Univ Dundee, Sch Life Sci, Div Signal Transduct Therapy, Dundee DD1 5EH, Scotland
关键词
D O I
10.1038/35096075
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Glycogen synthase kinase 3 (GSK3) was initially described as a key enzyme involved in glycogen metabolism, but is now known to regulate a diverse array of cell functions. The study of the substrate specificity and regulation of GSK3 activity has been important in the quest for therapeutic intervention.
引用
收藏
页码:769 / 776
页数:8
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