The renaissance of GSK3

被引：1333

作者：

Cohen, P ^{[1
]}

Frame, S

机构：

[1] Univ Dundee, Sch Life Sci, MRC, Prot Phosphorylat Unit, Dundee DD1 5EH, Scotland

[2] Univ Dundee, Sch Life Sci, Div Signal Transduct Therapy, Dundee DD1 5EH, Scotland

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2001年 / 2卷 / 10期

关键词：

D O I：

10.1038/35096075

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Glycogen synthase kinase 3 (GSK3) was initially described as a key enzyme involved in glycogen metabolism, but is now known to regulate a diverse array of cell functions. The study of the substrate specificity and regulation of GSK3 activity has been important in the quest for therapeutic intervention.

引用

页码：769 / 776

页数：8

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