A common class of nematode glutathione S-transferase (GST) revealed by the theoretical proteome of the model organism Caenorhabditis elegans

被引：28

作者：

Campbell, AM ^{[1
]}

Teesdale-Spittle, PH ^{[1
]}

Barrett, J ^{[1
]}

Liebau, E ^{[1
]}

Jefferies, JR ^{[1
]}

Brophy, PM ^{[1
]}

机构：

[1] Aberystwyth Univ, Inst Biol Sci, Aberystwyth SY23 3DA, Dyfed, Wales

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY | 2001年 / 128卷 / 04期

基金：

英国生物技术与生命科学研究理事会;

关键词：

Glutathione S-transferase; nematode; Heligmosomoides polygyrus; homology modelling; detoxification; Caenorhabditis elegans; proteome; genome verified;

D O I：

10.1016/S1096-4959(00)00360-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The genome verified C. elegans free-living nematode model is a new tool for investigating gene expression in human and animal nematode parasites. There is limited information on designating glutathione S-transferase (GST) to specific classes in lower invertebrates such as nematodes. Following cloning, amino acid sequence alignment, recombinant expression and Western blotting we provide evidence of a new GST class in nematodes or lower invertebrates. (C) 2001 Elsevier Science Inc. All rights reserved.

引用

页码：701 / 708

页数：8

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