The ETS-domain transcription factor family

被引:855
作者
Sharrocks, AD [1 ]
机构
[1] Univ Manchester, Sch Biol Sci, Manchester M13 9PT, Lancs, England
基金
英国惠康基金; 英国医学研究理事会;
关键词
D O I
10.1038/35099076
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
ETS-domain transcription-factor networks represent a model for how combinatorial gene expression is achieved. These transcription factors interact with a multitude of co-regulatory partners to elicit gene-specific responses and drive distinct biological processes. These proteins are controlled by a complex series of inter and intramolecular interactions, and signalling pathways impinge on these proteins to further regulate their action.
引用
收藏
页码:827 / 837
页数:11
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