OMA 2011: orthology inference among 1000 complete genomes

被引：153

作者：

Altenhoff, Adrian M. ^{[1
,2
]}

Schneider, Adrian ^{[3
]}

Gonnet, Gaston H. ^{[1
,2
]}

Dessimoz, Christophe ^{[1
,2
]}

机构：

[1] ETH, CH-8092 Zurich, Switzerland

[2] Swiss Inst Bioinformat, CH-8092 Zurich, Switzerland

[3] Univ Edinburgh, Inst Evolutionary Biol, Edinburgh EH9 3JT, Midlothian, Scotland

来源：

NUCLEIC ACIDS RESEARCH | 2011年 / 39卷

关键词：

DATABASE RESOURCES; NATIONAL-CENTER; IDENTIFICATION; BROWSER;

D O I：

10.1093/nar/gkq1238

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

OMA (Orthologous MAtrix) is a database that identifies orthologs among publicly available, complete genomes. Initiated in 2004, the project is at its 11th release. It now includes 1000 genomes, making it one of the largest resources of its kind. Here, we describe recent developments in terms of species covered; the algorithmic pipeline-in particular regarding the treatment of alternative splicing, and new features of the web (OMA Browser) and programming interface (SOAP API). In the second part, we review the various representations provided by OMA and their typical applications. The database is publicly accessible at http://omabrowser.org.

引用

页码：D289 / D294

页数：6

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