The Rotterdam Study: Objectives and design update

被引:302
作者
Hofman, Albert [1 ]
Breteler, Monique M. B.
van Duijn, Cornelia M.
Krestin, Gabriel P.
Pols, Huibert A.
Stricker, Bruno H. Ch.
Tiemeier, Henning
Uitterlinden, Andre G.
Vingerling, Johannes R.
Witteman, Jacqueline C. M.
机构
[1] Erasmus Sch Med, Dept Epidemiol & Biostat, Rotterdam, Netherlands
[2] Erasmus Sch Med, Dept Radiol, Rotterdam, Netherlands
[3] Erasmus Sch Med, Dept Internal Med, Rotterdam, Netherlands
[4] Erasmus Sch Med, Dept Ophthalmol, Rotterdam, Netherlands
关键词
Alzheimer disease; cohort study; dementia; diabetes; genome wide analysis; glaucoma; heart failure; macular degeneration; myocardial infarction; osteoporosis; Parkinson disease; pharmaco-epidemiology; stroke;
D O I
10.1007/s10654-007-9199-x
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of Rotterdam in the Netherlands. The study targets cardiovascular, neurological, ophthalmological and endocrine diseases. As of 2008 about 15,000 subjects aged 45 years or over comprise the Rotterdam Study cohort. The findings of the Rotterdam Study have been presented in some 600 research articles and reports (see http://www.epib.nl/rotterdamstudy). This article gives the reasons for the study and its design. It also presents a summary of the major findings and an update of the objectives and methods.
引用
收藏
页码:819 / 829
页数:11
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