Diabetes, left ventricular systolic dysfunction, and chronic heart failure

被引:182
作者
MacDonald, Michael R. [1 ]
Petrie, Mark C. [1 ]
Hawkins, Nathaniel M. [2 ]
Petrie, John R. [3 ]
Fisher, Miles [1 ]
McKelvie, Robert [4 ]
Aguilar, David [5 ]
Krum, Henry [6 ]
McMurray, John J. V. [7 ]
机构
[1] Glasgow Royal Infirm, Glasgow G4 0SF, Lanark, Scotland
[2] Aintree Cardiac Ctr, Liverpool, Merseyside, England
[3] Univ Dundee, Dundee, Scotland
[4] McMaster Univ, Hamilton, ON, Canada
[5] Baylor Coll Med, Houston, TX 77030 USA
[6] Monash Univ, Alfred Hosp, Melbourne, Vic 3181, Australia
[7] Univ Glasgow, Western Infirm, Glasgow G11 6NT, Lanark, Scotland
关键词
D O I
10.1093/eurheartj/ehn156
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Chronic heart failure (HF) and diabetes mellitus (DM) commonly coexist. Each condition increases the likelihood of developing the other, and when they occur together in the same patient the risk of morbidity and mortality increases markedly. We discuss the epidemiological overlap and consider the complex patho-physiological pathways linking the two diseases. The treatment of each condition is made more problematic by the presence of the other. We review the evidence-based treatment strategies and discuss the common problems faced by physicians when treating patients with both conditions. This article forms a comprehensive overview of a fascinating intersection between two common diseases.
引用
收藏
页码:1224 / 1240
页数:17
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