Evaluation of a Records-Review Surveillance System Used to Determine the Prevalence of Autism Spectrum Disorders

被引：35

作者：

Avchen, Rachel Nonkin ^{[1
]}

Wiggins, Lisa D. ^{[1
]}

Devine, Owen ^{[1
]}

Braun, Kim Van Naarden ^{[1
]}

Rice, Catherine ^{[1
]}

Hobson, Nancy C. ^{[2
]}

Schendel, Diana ^{[1
]}

Yeargin-Allsopp, Marshalyn ^{[1
]}

机构：

[1] Ctr Dis Control & Prevent, Dev Disabil Branch, Atlanta, GA 30333 USA

[2] Res Triangle Inst, Atlanta, GA USA

来源：

JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS | 2011年 / 41卷 / 02期

关键词：

Autism; Surveillance; Sensitivity; Specificity; Prevalence; TOTAL POPULATION; UNITED-STATES; CHILDREN; DIAGNOSIS; IDENTIFICATION;

D O I：

10.1007/s10803-010-1050-7

中图分类号：

B844 [发展心理学（人类心理学）];

学科分类号：

040202 ;

摘要：

We conducted the first study that estimates the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of a population-based autism spectrum disorders (ASD) surveillance system developed at the Centers for Disease Control and Prevention. The system employs a records-review methodology that yields ASD classification (case versus non-ASD case) and was compared with classification based on clinical examination. The study enrolled 177 children. Estimated specificity (0.96, [CI.95 = 0.94, 0.99]), PPV (0.79 [CI.95 = 0.66, 0.93]), and NPV (0.91 [CI.95 = 0.87, 0.96]) were high. Sensitivity was lower (0.60 [CI.95 = 0.45, 0.75]). Given diagnostic heterogeneity, and the broad array of ASD in the population, identifying children with ASD is challenging. Records-based surveillance yields a population-based estimate of ASD that is likely conservative.

引用

页码：227 / 236

页数：10