Methodology of brain perfusion imaging

被引:292
作者
Barbier, EL [1 ]
Lamalle, L [1 ]
Décorps, M [1 ]
机构
[1] CHU Michallon, INSERM U438, F-38043 Grenoble 9, France
关键词
cerebral blood volume; cerebral blood flow; mean transit time; transit time; magnetic resonance imaging; dynamic susceptibility contrast; contrast agent; bolus tracking; arterial spin labeling; arterial spin tagging; functional imaging; neuroimaging; review;
D O I
10.1002/jmri.1073
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Numerous techniques have been proposed in the last 15 years to measure various perfusion-related parameters in the brain. In particular, two approaches have proven extremely successful: injection of paramagnetic contrast agents for measuring cerebral blood volumes (CBV) and arterial spin labeling (ASL) for measuring cerebral blood flows (CBF). This review presents the methodology of the different magnetic resonance imaging (MRI) techniques in use for CBV and CBF measurements and briefly discusses their limitations and potentials. (C) 2001 Wiley-Liss, Inc.
引用
收藏
页码:496 / 520
页数:25
相关论文
共 287 条
[31]  
Bovee WMMJ, 1997, CELL MOL BIOL, V43, P675
[32]   Signal-to-noise analysis of cerebral blood volume maps from dynamic NMR imaging studies [J].
Boxerman, JL ;
Rosen, BR ;
Weisskoff, RM .
JMRI-JOURNAL OF MAGNETIC RESONANCE IMAGING, 1997, 7 (03) :528-537
[33]   THE INTRAVASCULAR CONTRIBUTION TO FMRI SIGNAL CHANGE - MONTE-CARLO MODELING AND DIFFUSION-WEIGHTED STUDIES IN-VIVO [J].
BOXERMAN, JL ;
BANDETTINI, PA ;
KWONG, KK ;
BAKER, JR ;
DAVIS, TL ;
ROSEN, BR ;
WEISSKOFF, RM .
MAGNETIC RESONANCE IN MEDICINE, 1995, 34 (01) :4-10
[34]   MR CONTRAST DUE TO INTRAVASCULAR MAGNETIC-SUSCEPTIBILITY PERTURBATIONS [J].
BOXERMAN, JL ;
HAMBERG, LM ;
ROSEN, BR ;
WEISSKOFF, RM .
MAGNETIC RESONANCE IN MEDICINE, 1995, 34 (04) :555-566
[35]   ACUTE TOXICITY OF A NUCLEAR-MAGNETIC-RESONANCE CEREBRAL BLOOD-FLOW INDICATOR IN CATS [J].
BRANCH, CA ;
EWING, JR ;
FAGAN, SC ;
GOLDBERG, DA ;
WELCH, KMA .
STROKE, 1990, 21 (08) :1172-1177
[36]   Magnetic resonance imaging of perfusion in rat cerebral 9L tumor after nicotinamide administration [J].
Brown, SL ;
Ewing, JR ;
Kolozsvary, A ;
Butt, S ;
Cao, Y ;
Kim, JH .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1999, 43 (03) :627-633
[37]   Regional cerebral blood flow determination using 133Xe and a standard rotating gamma-camera [J].
Bruyant, P ;
Sau, J ;
Mallet, JJ ;
Bonmartin, A .
COMPUTERS IN BIOLOGY AND MEDICINE, 1998, 28 (01) :27-45
[38]   Reperfusion after thrombolytic therapy of embolic stroke in the rat:: Magnetic resonance and biochemical imaging [J].
Busch, E ;
Krüger, K ;
Allegrini, PR ;
Kerskens, CM ;
Gyngell, ML ;
Hoehn-Berlage, M ;
Hossmann, KA .
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 1998, 18 (04) :407-418
[39]   A general kinetic model for quantitative perfusion imaging with arterial spin labeling [J].
Buxton, RB ;
Frank, LR ;
Wong, EC ;
Siewert, B ;
Warach, S ;
Edelman, RR .
MAGNETIC RESONANCE IN MEDICINE, 1998, 40 (03) :383-396
[40]  
Calamante F, 1999, MAGN RESON MED, V41, P479, DOI 10.1002/(SICI)1522-2594(199903)41:3<479::AID-MRM9>3.0.CO