Strong single-fiber sensory inputs to olfactory cortex: Implications for olfactory coding

被引:98
作者
Franks, KM [1 ]
Isaacson, JS [1 ]
机构
[1] Univ Calif San Diego, Sch Med, Dept Neurosci, La Jolla, CA 92093 USA
关键词
D O I
10.1016/j.neuron.2005.12.026
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Olfactory information is first encoded in a combinatorial fashion by olfactory bulb glomeruli, which individually represent distinct chemical features of odors. This information is then transmitted to piriform (olfactory) cortex, via axons of olfactory bulb mitral and tufted (M/T) cells, where it is presumed to form the odor percept. However, mechanisms governing the integration of sensory information in mammalian olfactory cortex are unclear. Here we show that single M/T cells can make powerful connections with cortical pyramidal cells, and coincident input from few M/T cells is sufficient to elicit spike output. These findings suggest that odor coding is broad and distributed in olfactory cortex.
引用
收藏
页码:357 / 363
页数:7
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