Intercellular adhesion, signalling and the cytoskeleton

被引：476

作者：

Jamora, C ^{[1
]}

Fuchs, E ^{[1
]}

机构：

[1] Univ Chicago, Howard Hughes Med Inst, Dept Mol Genet & Cell Biol, Chicago, IL 60637 USA

来源：

NATURE CELL BIOLOGY | 2002年 / 4卷 / 04期

关键词：

D O I：

10.1038/ncb0402-e101

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Connections between the cytoskeleton and intercellular junctions profoundly influence cell shape and motility. It is becoming increasingly clear that in addition to structural functions, components of the adhesion apparatus also possess signalling capabilities. Recent studies suggest that their dual function may provide the means to integrate changes in morphology and gene expression during tissue and organ development.

引用

页码：E101 / E108

页数：8

共 109 条

[11] Wnt signaling: a common theme in animal development [J].

Cadigan, KM ;

Nusse, R .

GENES & DEVELOPMENT, 1997, 11 (24) :3286-3305

[12] Plakoglobin suppresses epithelial proliferation and hair growth in vivo. [J].

Charpentier, E ;

Lavker, RM ;

Acquista, E ;

Cowin, P .

JOURNAL OF CELL BIOLOGY, 2000, 149 (02) :503-519

[13] Cadherin-mediated regulation of microtubule dynamics [J].

Chausovsky, A ;

Bershadsky, AD ;

Borisy, GG .

NATURE CELL BIOLOGY, 2000, 2 (11) :797-804

[14]

CHEN YT, 1994, J CELL BIOL, V4, P687

[15] Mice lacking desmocollin 1 show epidermal fragility accompanied by barrier defects and abnormal differentiation [J].

Chidgey, M ;

Brakebusch, C ;

Gustafsson, E ;

Cruchley, A ;

Hail, C ;

Kirk, S ;

Merritt, A ;

North, A ;

Tselepis, C ;

Hewitt, J ;

Byrne, C ;

Fassler, R ;

Garrod, D .

JOURNAL OF CELL BIOLOGY, 2001, 155 (05) :821-832

[16] FGF signaling regulates mesoderm cell fate specification and morphogenetic movement at the primitive streak [J].

Ciruna, B ;

Rossant, J .

DEVELOPMENTAL CELL, 2001, 1 (01) :37-49

[17] The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion [J].

Comijn, J ;

Berx, G ;

Vermassen, P ;

Verschueren, K ;

van Grunsven, L ;

Bruyneel, E ;

Mareel, M ;

Huylebroeck, D ;

van Roy, F .

MOLECULAR CELL, 2001, 7 (06) :1267-1278

[18]

DasGupta R, 1999, DEVELOPMENT, V126, P4557

[19] Binding to cadherins antagonizes the signaling activity of beta-catenin during axis formation in Xenopus [J].

Fagotto, F ;

Funayama, N ;

Gluck, U ;

Gumbiner, BM .

JOURNAL OF CELL BIOLOGY, 1996, 132 (06) :1105-1114

[20] At the roots of a never-ending cycle [J].

Fuchs, E ;

Merrill, BJ ;

Jamora, C ;

DasGupta, R .

DEVELOPMENTAL CELL, 2001, 1 (01) :13-25

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