Theta oscillations in the hippocampus

被引:2374
作者
Buzsáki, G
机构
[1] Rutgers State Univ, Ctr Mol & Behav Neurosci, Newark, NJ 07102 USA
[2] Neurol Inst New Jersey, Newark, NJ 07102 USA
关键词
D O I
10.1016/S0896-6273(02)00586-X
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Theta oscillations represent the "on-line" state of the hippocampus. The extracellular currents underlying theta waves are generated mainly by the entorhinal Input, CA3 (Schaffer) collaterals, and voltage-dependent Ca2+ currents in pyramidal cell dendrites. The rhythm is believed to be critical for temporal coding/ decoding of active neuronal ensembles and the modification of synaptic weights. Nevertheless, numerous critical issues regarding both the generation of theta oscillations and their functional significance remain challenges for future research.
引用
收藏
页码:325 / 340
页数:16
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