Three-dimensional structures and contexts associated with recurrent amino acid sequence patterns

被引：29

作者：

Han, KF

Bystroff, C

Baker, D

机构：

[1] UNIV WASHINGTON, DEPT BIOCHEM, SEATTLE, WA 98195 USA

[2] UNIV CALIF SAN FRANCISCO, SCH MED, GRAD GRP BIOPHYS, SAN FRANCISCO, CA 94143 USA

来源：

PROTEIN SCIENCE | 1997年 / 6卷 / 07期

关键词：

cluster analyses; protein folding; sequence motifs; structure production;

D O I：

10.1002/pro.5560060723

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We have used cluster analysis to identify recurring sequence patterns that transcend protein family boundaries. A subset of these patterns occur predominantly in a single type of local structure in proteins. Here we characterize the three-dimensional structures and contexts in which these sequence patterns occur, with particular attention to the interactions responsible for their structural selectivity.

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收藏

页码：1587 / 1590

页数：4

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