Dendritic cell derived cytokines in human natural killer cell cifferentiation anc activation

被引:45
作者
Chijioke, Obinna [1 ]
Muenz, Christian [1 ]
机构
[1] Univ Zurich, Inst Expt Immunol, Viral Immunobiol, CH-8057 Zurich, Switzerland
基金
瑞士国家科学基金会;
关键词
IL-18; IL-12; IL-15; IFN-alpha; immunological synapse; NKp30; DNAM-1; NK CELLS; CROSS-TALK; IFN-GAMMA; T-CELLS; LYMPH-NODES; SUPPRESSOR-CELLS; LANGERHANS CELLS; DISTINCT ROLES; DC MATURATION; STEADY-STATE;
D O I
10.3389/fimmu.2013.00365
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Dendritic cells (DCs) and natural killer (NK) cells shape each other's functions early during immune responses. DCs activate NK cells and NK cells can mature or kill DCs. In this review we will discuss which DC and NK cell subsets are mainly affected by this interaction, where these encounters might take place and which signals are exchanged. Finally, we will point out what the clinical benefit of understanding this interaction might be and how it changed our view on NK cells as innate lymphocytes.
引用
收藏
页数:7
相关论文
共 91 条
[1]   DC-NK cell cross talk as a novel CD4+ T-cell-independent pathway for antitumor CTL induction [J].
Adam, C ;
King, S ;
Allgeier, T ;
Braumüller, H ;
Lüking, C ;
Mysliwietz, J ;
Kriegeskorte, A ;
Busch, DH ;
Röcken, M ;
Mocikat, R .
BLOOD, 2005, 106 (01) :338-344
[2]   Analysis of NK cell/DC interaction in NK-type lymphoproliferative disease of granular lymphocytes (LDGL): role of DNAM-1 and NKp30 [J].
Balsamo, Mirna ;
Zambello, Renato ;
Teramo, Antonella ;
Pedrazzi, Marco ;
Sparatore, Bianca ;
Scordamaglia, Francesca ;
Pende, Danlela ;
Mingari, Maria Cristina ;
Moretta, Lorenzo ;
Moretta, Alessandro ;
Semenzato, Gianpietro ;
Vitale, Massimo .
EXPERIMENTAL HEMATOLOGY, 2009, 37 (10) :1167-1175
[3]   NK cells promote islet allograft tolerance via a perforin-dependent mechanism [J].
Beilke, JN ;
Kuhl, NR ;
Van Kaer, L ;
Gill, RG .
NATURE MEDICINE, 2005, 11 (10) :1059-1065
[4]   Dynamic behavior of NK cells during activation in lymph nodes [J].
Beuneu, Helene ;
Deguine, Jacques ;
Breart, Beatrice ;
Mandelboim, Ofer ;
Di Santo, James P. ;
Bousso, Philippe .
BLOOD, 2009, 114 (15) :3227-3234
[5]   NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRs [J].
Beziat, Vivien ;
Liu, Lisa L. ;
Malmberg, Jenny-Ann ;
Ivarsson, Martin A. ;
Sohlberg, Ebba ;
Bjorklund, Andreas T. ;
Retiere, Christelle ;
Sverremark-Ekstrom, Eva ;
Traherne, James ;
Ljungman, Per ;
Schaffer, Marie ;
Price, David A. ;
Trowsdale, John ;
Michaelsson, Jakob ;
Ljunggren, Hans-Gustaf ;
Malmberg, Karl-Johan .
BLOOD, 2013, 121 (14) :2678-2688
[6]   Primed Antigen-Specific CD4+ T Cells Are Required for NK Cell Activation In Vivo upon Leishmania major Infection [J].
Bihl, Franck ;
Pecheur, Julien ;
Breart, Beatrice ;
Poupon, Gwenola ;
Cazareth, Julie ;
Julia, Valerie ;
Glaichenhaus, Nicolas ;
Braud, Veronique M. .
JOURNAL OF IMMUNOLOGY, 2010, 185 (04) :2174-2181
[7]   Expression patterns of NKG2A, KIR, and CD57 define a process of CD56dim NK-cell differentiation uncoupled from NK-cell education [J].
Bjorkstrom, Niklas K. ;
Riese, Peggy ;
Heuts, Frank ;
Andersson, Sandra ;
Fauriat, Cyril ;
Ivarsson, Martin A. ;
Bjorklund, Andreas T. ;
Flodstrom-Tullberg, Malin ;
Michaelsson, Jakob ;
Rottenberg, Martin E. ;
Guzman, Carlos A. ;
Ljunggren, Hans-Gustaf ;
Malmberg, Karl-Johan .
BLOOD, 2010, 116 (19) :3853-3864
[8]   NK cell activation by dendritic cells (DCs) requires the formation of a synapse leading to IL-12 polarization in DCs [J].
Borg, C ;
Jalil, A ;
Laderach, D ;
Maruyama, K ;
Wakasugi, H ;
Charrier, S ;
Ryffel, B ;
Cambi, A ;
Figdor, C ;
Vainchenker, W ;
Galy, A ;
Caignard, A ;
Zitvogel, L .
BLOOD, 2004, 104 (10) :3267-3275
[9]   NK cell survival mediated through the regulatory synapse with human DCs requires IL-15Rα [J].
Brilot, Fabienne ;
Strowig, Till ;
Roberts, Susanne M. ;
Arrey, Frida ;
Muenz, Christian .
JOURNAL OF CLINICAL INVESTIGATION, 2007, 117 (11) :3316-3329
[10]   Natural killer and dendritic cell contact in lesional atopic dermatitis skin -: Malassezia-influenced cell interaction [J].
Buentke, E ;
Heffler, LC ;
Wilson, JL ;
Wallin, RPA ;
Löfman, C ;
Chambers, BJ ;
Ljunggren, HG ;
Scheynius, A .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2002, 119 (04) :850-857