Tackling both sides of the host-pathogen equation with Caenorhabditis elegans

被引：83

作者：

Ewbank, JJ ^{[1
]}

机构：

[1] Univ Mediterranee, CNRS, INSERM, Ctr Immunol Marseille Luminy, F-13288 Marseille 9, France

来源：

MICROBES AND INFECTION | 2002年 / 4卷 / 02期

关键词：

models; genetic; virulence; immunity; natural;

D O I：

10.1016/S1286-4579(01)01531-3

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

If one is interested in dissecting the complex interactions that exist between host and pathogen, the nematode worm Caenorhabditis elegans is perhaps not the first model host that comes to mind. In this review I will introduce 'the worm' and try to show how it is, in fact, well suited to the identification of universal virulence factors and holds great promise for the study of conserved mechanisms of innate immunity. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.

引用

页码：247 / 256

页数：10

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