Vascular endothelial growth factor and angiopoietins in focal cerebral ischemia

被引：191

作者：

Zhang, ZG

Chopp, M

机构：

[1] Henry Ford Hlth Sci Ctr, Dept Neurol, Detroit, MI 48202 USA

[2] Oakland Univ, Dept Phys, Rochester, MI USA

来源：

TRENDS IN CARDIOVASCULAR MEDICINE | 2002年 / 12卷 / 02期

关键词：

D O I：

10.1016/S1050-1738(01)00149-9

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A growing body of evidence indicates that vascular growth factors and their receptors are activated after stroke, and these factors may contribute to ischemic cell damage and to angiogenesis during recovery from stroke. In this review, we focus on recent evidence for roles of vascular endothelial growth factor (VEGF) and angiopoietin 1 (Ang 1) in blood-brain barrier (BBB) leakage and angiogenesis after focal cerebral ischemia. (Trends Cardiovasc Med 2002; 12:62-66). (C) 2002, Elsevier Science Inc.

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页码：62 / 66

页数：5

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