Clone DB: an integrated NCBI resource for clone-associated data

被引：11

作者：

Schneider, Valerie A. ^{[1
]}

Chen, Hsiu-Chuan ^{[1
]}

Clausen, Cliff ^{[1
]}

Meric, Peter A. ^{[1
]}

Zhou, Zhigang ^{[1
]}

Bouk, Nathan ^{[1
]}

Husain, Nora ^{[1
]}

Maglott, Donna R. ^{[1
]}

Church, Deanna M. ^{[1
]}

机构：

[1] NIH, Natl Ctr Biotechnol Informat, Natl Lib Med, Bethesda, MD 20892 USA

来源：

NUCLEIC ACIDS RESEARCH | 2013年 / 41卷 / D1期

基金：

美国国家卫生研究院;

关键词：

STRUCTURAL VARIATION; GENOME SEQUENCE; MOUSE; GENE; TRAP; CHROMOSOMES; WINDOW;

D O I：

10.1093/nar/gks1164

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The National Center for Biotechnology Information (NCBI) Clone DB (http://www.ncbi.nlm.nih.gov/clone/) is an integrated resource providing information about and facilitating access to clones, which serve as valuable research reagents in many fields, including genome sequencing and variation analysis. Clone DB represents an expansion and replacement of the former NCBI Clone Registry and has records for genomic and cell-based libraries and clones representing more than 100 different eukaryotic taxa. Records provide details of library construction, associated sequences, map positions and information about resource distribution. Clone DB is indexed in the NCBI Entrez system and can be queried by fields that include organism, clone name, gene name and sequence identifier. Whenever possible, genomic clones are mapped to reference assemblies and their map positions provided in clone records. Clones mapping to specific genomic regions can also be searched for using the NCBI Clone Finder tool, which accepts queries based on sequence coordinates or features such as gene or transcript names. Clone DB makes reports of library, clone and placement data on its FTP site available for download. With Clone DB, users now have available to them a centralized resource that provides them with the tools they will need to make use of these important research reagents.

引用

页码：D1070 / D1078

页数：9

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