进展性脑卒中危险因素的临床分析

被引:47
作者
王玮
机构
[1] 首都医科大学附属北京朝阳医院神经内科
关键词
进展性脑卒中; 危险预测因素;
D O I
暂无
中图分类号
R743.3 [急性脑血管疾病(中风)];
学科分类号
1002 ;
摘要
目的探讨进展性脑卒中发病的相关危险因素及预测强度。方法收集脑卒中患者234例,其中进展性脑卒中(SIP)患者116例,非进展性脑卒中(NSIP)患者118例。详细记录两组患者的高血压病史、糖尿病史、颈动脉狭窄、入院血糖、血浆同型半胱氨酸(Hcy)浓度以及次日空腹血脂情况,包括甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)和低密度脂蛋白胆固醇(LDL-C)值。结果两组病例高血压病史、糖尿病史、颈动脉狭窄以及入院次日空腹血糖、Hcy值、空腹TC、TG、LDL-C比较差异有统计学意义(P<0.05),Logistic回归分析结果显示高血压病史、空腹血糖、颈动脉狭窄、hs-CRP和Hcy等指标是SIP的独立危险因素。结论 SIP的发病是多因素、多机制共同作用的过程,既往高血压和发生脑卒中后骤然降压、持续高血糖、大动脉硬化及狭窄、Hcy以及高血脂、高凝状态等构成了缺血性脑卒中进展的主要因素。
引用
收藏
页码:5811 / 5814
页数:4
相关论文
共 18 条
[11]  
The potent different risk factors for cerebral infarction in young patients with and without type 2 diabetes: Subanalysis of the Young Cerebral Infarction Study (YCIS)[J] . Bin Zhang,Cong Gao,Qinghua Hou,Jianrui Yin,Longchang Xie,Shuxiang Pu,Yonghong Yi,Qingchun Gao.Atherosclerosis . 2011 (1)
[12]   Monocyte chemoattractant protein-1 is associated with silent cerebral infarction in patients on haemodialysis [J].
Uchida, E. ;
Anan, F. ;
Masaki, T. ;
Kaneda, K. ;
Nawata, T. ;
Eshima, N. ;
Saikawa, T. ;
Yoshimatsu, H. .
INTERNAL MEDICINE JOURNAL, 2012, 42 (01) :29-34
[13]   Early cerebral infarction as a risk factor for poor outcome after aneurysmal subarachnoid haemorrhage [J].
Juvela, S. ;
Siironen, J. .
EUROPEAN JOURNAL OF NEUROLOGY, 2012, 19 (02) :332-339
[14]   Effects of tetrahydrobiopterin on cerebral infarction after transient focal ischemia in rats [J].
Tang, Ling-Ling ;
Zheng, Jie-Sheng .
NEUROLOGICAL RESEARCH, 2011, 33 (10) :1064-1067
[15]  
Neurobehavioural deficits correlate with the cerebral infarction volume of stroke animals: A comparative study on ischaemia-reperfusion and photothrombosis models[J] . Byong-il Choi,Dongsun Park,Sun Hee Lee,Dae-Kwon Bae,Goeun Yang,Yun-Hui Yang,Tae Kyun Kim,Ehn-Kyoung Choi,Hwa-Jeong Lee,Kyung-Chul Choi,Sang-Seop Nahm,Yun-Bae Kim.Environmental Toxicology and Pharmacology . 2011 (1)
[16]  
The Copenhagen Stroke Study experience[J] . Journal of Stroke and Cerebrovascular Diseases . 1996 (1)
[17]   STROKE-IN-PROGRESSION [J].
GAUTIER, JC .
STROKE, 1985, 16 (04) :729-733
[18]   HEPARIN FOR LACUNAR STROKE IN PROGRESSION [J].
DOBKIN, BH .
STROKE, 1983, 14 (03) :421-423