自噬与血管衰老的研究进展

被引：2

作者：

马懿

吴赛珠

龚勋

彭文杰

汤敏

钟元林

汤展

机构：

[1] 南方医科大学南方医院心内科

来源：

中国老年学杂志 | 2014年 / 34卷 / 19期

关键词：

自噬; 衰老; 血管内皮细胞; 血管平滑肌细胞;

D O I：

暂无

中图分类号：

R363 [病理生理学];

学科分类号：

100104 ;

摘要：

<正>自噬是由细胞质起源的自噬体与溶酶体融合降解胞内异常分子和长寿命蛋白的过程,是一种特殊分解代谢途径。它在细胞代谢、存活与分化等方面都具有重要作用。当前社会正朝向老龄化社会演变,关注老龄化相关疾病的研究显得格外重要。随着细胞生物科学与老年医学的相互交叉发展,自噬在老年性心血管疾病、神经退行性疾病、脏器衰老等方面的研究中取得进展。研究已发现通过对自噬调控能够对血管组成细胞的增殖、分化和转归起到重要的调控作用。本文对自噬与血管

引用

页码：5609 / 5612

页数：4

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