缺血性卒中预防中抗血小板药抵抗的应对策略

被引:2
作者
马启荣
王雁
机构
[1] 青岛大学附属医院神经内科
关键词
卒中; 脑缺血; 抗血小板聚集药; 阿司匹林; 氯吡格雷; 抗药性;
D O I
暂无
中图分类号
R743.3 [急性脑血管疾病(中风)];
学科分类号
1002 ;
摘要
阿司匹林和氯吡格雷被广泛应用于心脑血管病的防治。尽管部分患者接受抗血小板治疗,但仍会经历缺血性事件,这种现象被称为抗血小板药物抵抗。文章对缺血性卒中预防中抗血小板药物抵抗的应对策略进行了综述。
引用
收藏
页码:1123 / 1127
页数:5
相关论文
共 23 条
[1]  
维持性血液透析患者阿司匹林抵抗的发生率及相关因素[J]. 张春华,崔太根,赵素梅,王世相,张小东.中华内科杂志. 2014 (03)
[2]   Associations of P2Y12R gene polymorphisms with susceptibility to coronary heart disease and clinical efficacy of antiplatelet treatment with clopidogrel [J].
Yang, Hong-Hui ;
Chen, Yan ;
Gao, Chuan-Yu .
CARDIOVASCULAR THERAPEUTICS, 2016, 34 (06) :460-467
[3]   Does high serum uric acid level cause aspirin resistance? [J].
Yildiz, Bekir S. ;
Ozkan, Emel ;
Esin, Fatma ;
Alihanoglu, Yusuf I. ;
Ozkan, Hayrettin ;
Bilgin, Murat ;
Kilic, Ismail D. ;
Ergin, Ahmet ;
Kaftan, Havane A. ;
Evrengul, Harun .
BLOOD COAGULATION & FIBRINOLYSIS, 2016, 27 (04) :412-418
[4]  
Prasugrel in Clopidogrel Nonresponders Undergoing Percutaneous Coronary Intervention[J] . Renato Valenti,Rossella Marcucci,Vincenzo Comito,Marco Marrani,Giulia Cantini,Angela Migliorini,Guido Parodi,Gian Franco Gensini,Rosanna Abbate,David Antoniucci.JACC: Cardiovascular Interventions . 2015 (12)
[5]   Risk factors for clopidogrel resistance in patients with ischemic cerebral infarction and the correlation with ABCB1 gene rs1045642 polymorphism [J].
Su, Jun-Feng ;
Hu, Xiao-Hui ;
Li, Cheng-Yan .
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2015, 9 (01) :267-271
[6]  
Multiple daily doses of acetyl‐salicylic acid (ASA) overcome reduced platelet response to once‐daily ASA after coronary artery bypass graft surgery: a pilot randomized controlled trial[J] . J. S. Paikin,J. Hirsh,J. S. Ginsberg,J. I. Weitz,N. C. Chan,R. P. Whitlock,G. Pare,M. Johnston,J. W. Eikelboom.J Thromb Haemost . 2015 (3)
[7]  
Laboratory Aspirin Resistance Reversibility in Diabetic Patients: a Pilot Study Using Different Pharmaceutical Formulations[J] . Roberto Grimaldi,Marta Bisi,Enrica Lonni,Eloise Beggiato,Alessandra Valpreda,Marco Francesco Lococo,Enrico Dosio,Davide Giacomo Presutti,Milena Tagliabue,Fiorenzo Gaita.Cardiovascular Drugs and Therapy . 2014 (4)
[8]   Non-HDL cholesterol is an independent risk factor for aspirin resistance in obese patients with type 2 diabetes [J].
Kim, Jong Dai ;
Park, Cheol-Young ;
Ahn, Kue Jeong ;
Cho, Jae Hyoung ;
Choi, Kyung Mook ;
Kang, Jun Goo ;
Kim, Jae Hyeon ;
Lee, Ki Young ;
Lee, Byung Wan ;
Mok, Ji Oh ;
Moon, Min Kyong ;
Park, Joong Yeol ;
Park, Sung Woo .
ATHEROSCLEROSIS, 2014, 234 (01) :146-151
[9]   Effect of cilostazol addition or clopidogrel doubling on platelet function profiles in diabetic patients undergoing a percutaneous coronary intervention [J].
Ha, Sang Jin ;
Kim, Soo-Joong ;
Hwang, Seok-Jae ;
Woo, Jong Shin ;
Kim, Weon ;
Kim, Woo-Shik ;
Kim, Kwon Sam ;
Kim, Myeong Kon .
CORONARY ARTERY DISEASE, 2013, 24 (08) :690-697
[10]   Interaction Between vWF Levels and Aspirin Resistance in Ischemic Stroke Patients [J].
Arslan, Yildiz ;
Yoldas, Tahir Kurtulus ;
Zorlu, Yasar .
TRANSLATIONAL STROKE RESEARCH, 2013, 4 (05) :484-487