血小板糖蛋白Ⅱb/Ⅲa受体拮抗剂在缺血性卒中中的应用与前景

被引：8

作者：

叶妮

张临洪

机构：

[1] 武汉市中心医院神经内科

来源：

国际脑血管病杂志 | 2006年 / 06期

关键词：

血小板糖蛋白Ⅱb/Ⅲa受体拮抗剂; 缺血性卒中; 溶栓; 颈动脉血管成形术; 支架置入术;

D O I：

暂无

中图分类号：

R743.3 [急性脑血管疾病（中风）];

学科分类号：

1002 ;

摘要：

血小板糖蛋白Ⅱb/Ⅲa受体拮抗剂是一类新型抗血小板药。文章从血小板糖蛋白Ⅱb/Ⅲa受体拮抗剂与溶栓药联合应用、在颈动脉血管成形和支架置入术中的应用以及单独使用等方面探讨了其在缺血性卒中中的应用与前景。

引用

页码：432 / 436

页数：5

共 11 条

[1] Multimodal therapy for the treatment of severe ischemic stroke combining GPIIb/IIIa antagonists and angioplasty after failure of thrombolysis [J].

Abou-Chebl, A ;

Bajzer, CT ;

Krieger, DW ;

Furlan, AJ ;

Yadav, JS .

STROKE, 2005, 36 (10) :2286-2288

[2]

Extending Reperfusion Therapy for Acute Ischemic Stroke: Emerging Pharmacological, Mechanical, and Imaging Strategies[J] . Carlos A. Molina,Jeffrey L. Saver.Stroke . 2005 (10)

[3] Partial rescue of the perfusion deficit area by thrombolysis [J].

Seitz, RJ ;

Meisel, S ;

Moll, M ;

Wittsack, HJ ;

Junghans, U ;

Siebler, M .

JOURNAL OF MAGNETIC RESONANCE IMAGING, 2005, 22 (02) :199-205

[4]

Stroke Review: Advances in Interventional Neuroradiology 2004[J] . David Pelz,Tommy Andersson,Pedro Lylyk,Makoto Negoro,Michael Soderman.Stroke . 2005 (2)

[5] Comparison of the safety and efficacy of emboli prevention devices versus platelet glycoprotein IIb/IIIa inhibition during carotid stenting [J].

Chan, AW ;

Yadav, JS ;

Bhatt, DL ;

Bajzer, CT ;

Gum, PA ;

Roffi, M ;

Cho, L ;

Agah, R ;

Topol, EJ .

AMERICAN JOURNAL OF CARDIOLOGY, 2005, 95 (06) :791-795

[6]

FK419, a Novel Nonpeptide GPIIb/IIIa Antagonist, Restores Microvascular Patency and Improves Outcome in the Guinea-Pig Middle Cerebral Artery Thrombotic Occlusion Model: Comparison with Tirofiban[J] . Akira Moriguchi,Masashi Maeda,Kayoko Mihara,Toshiaki Aoki,Nobuya Matsuoka,Seitaro Mutoh.Journal of Cerebral Blood Flow & Metabolism . 2005 (1)

[7] Effect of loading with Clopidogrel at the time of coronary stenting on platelet aggregation and glycoprotein IIb/IIIa expression and platelet-leukocyte aggregate formation [J].

Gurbel, PA ;

Malinin, AI ;

Callahan, KP ;

Serebruany, VL ;

O'Connor, CM .

AMERICAN JOURNAL OF CARDIOLOGY, 2002, 90 (03) :312-+

[8] The GPIIb/IIIa antagonist eptifibatide markedly potentiates platelet-leukocyte interaction and tissue factor expression following platelet activation in whole blood in vitro [J].

Scholz, T ;

Zhao, L ;

Temmler, U ;

Bath, P ;

Heptinstall, S ;

Lösche, W .

PLATELETS, 2002, 13 (07) :401-406

[9] Complications of oral antiplatelet medications [J].

Van De Graaff E. ;

Steinhubl S.R. .

Current Cardiology Reports, 2001, 3 (5) :371-379

[10]

Clinical challenges of platelet glycoprotein IIb/IIIa receptor inhibitor therapy: Bleeding, reversal, thrombocytopenia, and retreatment[J] . James E Tcheng.American Heart Journal . 2000 (2)

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