ACYCLIC STEREOSELECTION .4. ASSIGNMENT OF STEREOSTRUCTURE TO BETA-HYDROXYCARBONYL COMPOUNDS BY C-13 NUCLEAR MAGNETIC-RESONANCE

被引：242

作者：

HEATHCOCK, CH

PIRRUNG, MC

SOHN, JE

机构：

[1] Department of Chemistry, University of California, Berkeley

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1979年 / 44卷 / 24期

关键词：

D O I：

10.1021/jo01338a015

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

13C NMR spectra for over 40 sets of β-hydroxycarbonyl compounds possessing diastereoisomerism were recorded. Empirical observations were made which allow the assignment of stereostructure to these compounds. A model for the preferred conformations of these molecules was developed which accounts for the observed chemical shift trends. © 1979, American Chemical Society. All rights reserved.

引用

页码：4294 / 4299

页数：6

共 21 条

[11] SYNTHESIS OF MACROLIDE ANTIBIOTICS .1. STEREOSPECIFIC ADDITION OF METHYLLITHIUM AND METHYLMAGNESIUM IODIDE TO METHYL ALPHA-D-XYLO-HEXOPYRANOSID-4-ULOSE DERIVATIVES - DETERMINATION OF CONFIGURATION AT BRANCHING CARBON-ATOM BY C-13 NUCLEAR MAGNETIC-RESONANCE SPECTROSCOPY [J].