HUMAN IMMUNODEFICIENCY VIRUS-TYPE-1 (HIV-1) AND THE BRAIN

被引：81

作者：

GRANT, I ^{[1
]}

HEATON, RK ^{[1
]}

机构：

[1] VET ADM MED CTR, SAN DIEGO, CA USA

来源：

JOURNAL OF CONSULTING AND CLINICAL PSYCHOLOGY | 1990年 / 58卷 / 01期

关键词：

D O I：

10.1037/0022-006X.58.1.22

中图分类号：

B849 [应用心理学];

学科分类号：

040203 ;

摘要：

Infection with human immunodeficiency virus Type-1 (HIV-1), the causative agent of AIDS, can be associated with central nervous system as well as immune system disease. Advanced AIDS can be complicated by a dementia. Short of frank dementia, many AIDS patients manifest neuropsychological (NP) impairment including disturbance in speeded information processing, abstraction, learning, and recall. Data conflict on whether medically asymptomatic HIV-1 carriers have subtle NP deficits. Variations in tests chosen, criterion specification, and sample selection may all be contributing to disparate results. Longitudinal research is needed, and this should examine representative samples of HIV-1 seropositive individuals for whom approximate date of serocon version is known and in whom sources of comorbidity (e.g., drug abuse, concurrent infections, CNS injuries) can be specified.

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页码：22 / 30

页数：9

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