THE LIPOPROTEIN LIPASE-ENCODING HUMAN GENE - SEQUENCE FROM INTRON-6 TO INTRON-9 AND PRESENCE IN INTRON-7 OF A 40-MILLION-YEAR-OLD ALU SEQUENCE

被引：19

作者：

CHUAT, JC

RAISONNIER, A

ETIENNE, J

GALIBERT, F

机构：

[1] UNIV PARIS 06, BIOCHIM LAB 507, 27 RUE CHALIGNY, F-75571 PARIS 12, FRANCE

[2] HOP ST LOUIS, CTR HAYEM, HEMATOL EXPTL LAB, F-75010 PARIS, FRANCE

来源：

GENE | 1992年 / 110卷 / 02期

关键词：

RECOMBINANT DNA; NUCLEOTIDE SEQUENCING; TRIGLYCERIDES; FATTY ACIDS; ILLEGITIMATE RECOMBINATION; PHYLOGENY; EXONS; PATHOLOGY; HYPERCHYLOMICRONEMIA;

D O I：

10.1016/0378-1119(92)90658-C

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The complete nucleotide sequence of the 3877-bp segment spanning the 3' region of intron-6 to the 5' region of intron-9 of the human lipoprotein lipase (LPL)-encoding ten-exon gene, LPL, is reported. An Alu repeat present in intron-7 was found by sequence analysis to belong to the 40-55-million-year-old Alu-Se subclass.

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收藏

页码：257 / 261

页数：5

相关论文

共 17 条

[1] DEFECTIVE ENZYME PROTEIN IN LIPOPROTEIN-LIPASE DEFICIENCY [J].

AUWERX, JH ;

BABIRAK, SP ;

FUJIMOTO, WY ;

IVERIUS, PH ;

BRUNZELL, JD .

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 1989, 19 (05) :433-437

[2] SOURCES AND EVOLUTION OF HUMAN ALU REPEATED SEQUENCES [J].

BRITTEN, RJ ;

BARON, WF ;

STOUT, DB ;

DAVIDSON, EH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (13) :4770-4774

[3] STRUCTURE OF THE HUMAN LIPOPROTEIN-LIPASE GENE [J].

DEEB, SS ;

PENG, RL .

BIOCHEMISTRY, 1989, 28 (10) :4132-4135

[4]

DEVLIN RH, 1990, AM J HUM GENET, V46, P112

[5] ON THE HIGH CONSERVATION OF THE HUMAN C-MYC 1ST EXON [J].

ELADARI, ME ;

SYED, SH ;

GUILHOT, S ;

DAURIOL, L ;

GALIBERT, F .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1986, 140 (01) :313-319

[6] EVIDENCE FOR HEPATIC ORIGIN OF A CANINE POST-HEPARIN PLASMA TRIGLYCERIDE LIPASE [J].

GRETEN, H ;

SNIDERMAN, AD ;

CHANDLER, JG ;

STEINBERG, D ;

BROWN, WV .

FEBS LETTERS, 1974, 42 (02) :157-160

[7]

GROFFEN J, 1989, PROG NUCLEIC ACID RE, V36, P281

[8]

HATA A, 1990, AM J HUM GENET, V47, P721

[9] A FUNDAMENTAL DIVISION IN THE ALU FAMILY OF REPEATED SEQUENCES [J].

JURKA, J ;

SMITH, T .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (13) :4775-4778

[10] ORGANIZATION OF THE HUMAN LIPOPROTEIN-LIPASE GENE AND EVOLUTION OF THE LIPASE GENE FAMILY [J].

KIRCHGESSNER, TG ;

CHUAT, JC ;

HEINZMANN, C ;

ETIENNE, J ;

GUILHOT, S ;

SVENSON, K ;

AMEIS, D ;

PILON, C ;

DAURIOL, L ;

ANDALIBI, A ;

SCHOTZ, MC ;

GALIBERT, F ;

LUSIS, AJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (24) :9647-9651