INTRONS INCREASE TRANSCRIPTIONAL EFFICIENCY IN TRANSGENIC MICE

被引：649

作者：

BRINSTER, RL

ALLEN, JM

BEHRINGER, RR

GELINAS, RE

PALMITER, RD

机构：

[1] UNIV WASHINGTON,HOWARD HUGHES MED INST,SEATTLE,WA 98195

[2] UNIV WASHINGTON,DEPT BIOCHEM SL15,SEATTLE,WA 98195

[3] FRED HUTCHINSON CANC RES CTR,DEPT MOLEC MED,SEATTLE,WA 98104

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1988年 / 85卷 / 03期

关键词：

D O I：

10.1073/pnas.85.3.836

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：836 / 840

页数：5

共 41 条

[21] SPLICING AND THE FORMATION OF STABLE RNA [J].

HAMER, DH ;

LEDER, P .

CELL, 1979, 18 (04) :1299-1302

[22] THE RAT ELASTASE-I REGULATORY ELEMENT IS AN ENHANCER THAT DIRECTS CORRECT CELL SPECIFICITY AND DEVELOPMENTAL ONSET OF EXPRESSION IN TRANSGENIC MICE [J].

HAMMER, RE ;

SWIFT, GH ;

ORNITZ, DM ;

QUAIFE, CJ ;

PALMITER, RD ;

BRINSTER, RL ;

MACDONALD, RJ .

MOLECULAR AND CELLULAR BIOLOGY, 1987, 7 (08) :2956-2967

[23] TISSUE-SPECIFIC EXPRESSION OF THE HUMAN GROWTH-HORMONE GENE IS CONFERRED IN PART BY THE BINDING OF A SPECIFIC TRANS-ACTING FACTOR [J].

LEFEVRE, C ;

IMAGAWA, M ;

DANA, S ;

GRINDLAY, J ;

BODNER, M ;

KARIN, M .

EMBO JOURNAL, 1987, 6 (04) :971-981

[24] COMPLEX TRANSCRIPTIONAL UNITS - DIVERSITY IN GENE-EXPRESSION BY ALTERNATIVE RNA PROCESSING [J].

LEFF, SE ;

ROSENFELD, MG ;

EVANS, RM .

ANNUAL REVIEW OF BIOCHEMISTRY, 1986, 55 :1091-1117

[25]

MCKNIGHT GS, 1979, J BIOL CHEM, V254, P9050

[26] EXPRESSION OF A BACTERIAL GENE IN MAMMALIAN-CELLS [J].

MULLIGAN, RC ;

BERG, P .

SCIENCE, 1980, 209 (4463) :1422-1427

[27]

MULVIHILL ER, 1977, J BIOL CHEM, V252, P2060

[28] RELATIONSHIP BETWEEN THE TOTAL SIZE OF EXONS AND INTRONS IN PROTEIN-CODING GENES OF HIGHER EUKARYOTES [J].

NAORA, H ;

DEACON, NJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (20) :6196-6200

[29] DISCRETE CIS-ACTIVE GENOMIC SEQUENCES DICTATE THE PITUITARY CELL TYPE-SPECIFIC EXPRESSION OF RAT PROLACTIN AND GROWTH-HORMONE GENES [J].

NELSON, C ;

CRENSHAW, EB ;

FRANCO, R ;

LIRA, SA ;

ALBERT, VR ;

EVANS, RM ;

ROSENFELD, MG .

NATURE, 1986, 322 (6079) :557-562

[30] A TEST FOR INTRON FUNCTION IN THE YEAST ACTIN GENE [J].

NG, R ;

DOMDEY, H ;

LARSON, G ;

ROSSI, JJ ;

ABELSON, J .

NATURE, 1985, 314 (6007) :183-184

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