SIGNAL TRANSDUCTION THROUGH CD4 RECEPTORS - STIMULATORY VS INHIBITORY ACTIVITY IS REGULATED BY CD4 PROXIMITY TO THE CD3/T CELL-RECEPTOR

被引：225

作者：

LEDBETTER, JA

JUNE, CH

RABINOVITCH, PS

GROSSMANN, A

TSU, TT

IMBODEN, JB

机构：

[1] VET ADM MED CTR,SAN FRANCISCO,CA 94121

[2] UNIV WASHINGTON,DEPT PATHOL,SEATTLE,WA 98195

[3] USN,MED RES INST,BETHESDA,MD 20814

[4] UNIV CALIF SAN FRANCISCO,DEPT MED,SAN FRANCISCO,CA 94143

来源：

EUROPEAN JOURNAL OF IMMUNOLOGY | 1988年 / 18卷 / 04期

关键词：

D O I：

10.1002/eji.1830180406

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

引用

页码：525 / 532

页数：8

共 50 条

[11]

GREENSTEIN JL, 1987, FED PROC, V46, P313

[12]

HANSEN JA, 1984, HUMAN LEUKOCYTE MARK, P195

[13]

HARDY RR, 1986, HDB EXPT IMMUNOLOGY, pCH31

[14] ALTERATIONS IN T4 (CD4) PROTEIN AND MESSENGER-RNA SYNTHESIS IN CELLS INFECTED WITH HIV [J].

HOXIE, JA ;

ALPERS, JD ;

RACKOWSKI, JL ;

HUEBNER, K ;

HAGGARTY, BS ;

CEDARBAUM, AJ ;

REED, JC .

SCIENCE, 1986, 234 (4780) :1123-1127

[15]

IMBODEN J, 1987, J IMMUNOL, V138, P1322

[16] TRANSMEMBRANE SIGNALING BY THE T-CELL ANTIGEN RECEPTOR - PERTURBATION OF THE T3-ANTIGEN RECEPTOR COMPLEX GENERATES INOSITOL PHOSPHATES AND RELEASES CALCIUM-IONS FROM INTRACELLULAR STORES [J].

IMBODEN, JB ;

STOBO, JD .

JOURNAL OF EXPERIMENTAL MEDICINE, 1985, 161 (03) :446-456

[17] T-CELL PROLIFERATION INVOLVING THE CD28 PATHWAY IS ASSOCIATED WITH CYCLOSPORINE-RESISTANT INTERLEUKIN-2 GENE-EXPRESSION [J].

JUNE, CH ;

LEDBETTER, JA ;

GILLESPIE, MM ;

LINDSTEN, T ;

THOMPSON, CB .

MOLECULAR AND CELLULAR BIOLOGY, 1987, 7 (12) :4472-4481

[18]

KLATZMANN E, 1984, NATURE, V312, P1120

[19] FUNCTIONAL REGIONS OF THE ENVELOPE GLYCOPROTEIN OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 [J].

KOWALSKI, M ;

POTZ, J ;

BASIRIPOUR, L ;

DORFMAN, T ;

WEI, CG ;

TERWILLIGER, E ;

DAYTON, A ;

ROSEN, C ;

HASELTINE, W ;

SODROSKI, J .

SCIENCE, 1987, 237 (4820) :1351-1355

[20] COCLUSTERING OF CD4 (L3T4) MOLECULE WITH THE T-CELL RECEPTOR IS INDUCED BY SPECIFIC DIRECT INTERACTION OF HELPER T-CELLS AND ANTIGEN-PRESENTING CELLS [J].

KUPFER, A ;

SINGER, SJ ;

JANEWAY, CA ;

SWAIN, SL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (16) :5888-5892

← 1 2 3 4 5 →