CONTROL OF OLIGOMERIC ENZYME THERMOSTABILITY BY PROTEIN ENGINEERING

被引：129

作者：

AHERN, TJ

CASAL, JI

PETSKO, GA

KLIBANOV, AM

机构：

[1] MIT,DEPT APPL BIOL SCI,CAMBRIDGE,MA 02139

[2] MIT,DEPT CHEM,CAMBRIDGE,MA 02139

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1987年 / 84卷 / 03期

关键词：

D O I：

10.1073/pnas.84.3.675

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：675 / 679

页数：5

共 32 条

[21] PH-DEPENDENCE OF TRIOSE PHOSPHATE ISOMERASE REACTION [J].

PLAUT, B ;

KNOWLES, JR .

BIOCHEMICAL JOURNAL, 1972, 129 (02) :311-&

[22] EFFICIENT CORRECTION OF A MUTATION BY USE OF CHEMICALLY SYNTHESIZED DNA [J].

RAZIN, A ;

HIROSE, T ;

ITAKURA, K ;

RIGGS, AD .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1978, 75 (09) :4268-4270

[23] DIHYDROXYACETONE PHOSPHATE - ITS STRUCTURE AND REACTIVITY WITH ALPHA-GLYCEROPHOSPHATE DEHYDROGENASE, ALDOLASE AND TRIOSE PHOSPHATE ISOMERASE AND SOME POSSIBLE METABOLIC IMPLICATIONS [J].

REYNOLDS, SJ ;

YATES, DW ;

POGSON, CI .

BIOCHEMICAL JOURNAL, 1971, 122 (03) :285-&

[24]

RIDDLES PW, 1983, METHOD ENZYMOL, V91, P49

[25] DNA SEQUENCING WITH CHAIN-TERMINATING INHIBITORS [J].

SANGER, F ;

NICKLEN, S ;

COULSON, AR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1977, 74 (12) :5463-5467

[26] ACTIVE-SITE OF TRIOSEPHOSPHATE ISOMERASE - INVITRO MUTAGENESIS AND CHARACTERIZATION OF AN ALTERED ENZYME [J].

STRAUS, D ;

RAINES, R ;

KAWASHIMA, E ;

KNOWLES, JR ;

GILBERT, W .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (08) :2272-2276

[27] DIRECTED MUTAGENESIS OF DIHYDROFOLATE-REDUCTASE [J].

VILLAFRANCA, JE ;

HOWELL, EE ;

VOET, DH ;

STROBEL, MS ;

OGDEN, RC ;

ABELSON, JN ;

KRAUT, J .

SCIENCE, 1983, 222 (4625) :782-788

[28] REFOLDING OF TRIOSE PHOSPHATE ISOMERASE [J].

WALEY, SG .

BIOCHEMICAL JOURNAL, 1973, 135 (01) :165-172

[29] A LARGE INCREASE IN ENZYME SUBSTRATE AFFINITY BY PROTEIN ENGINEERING [J].

WILKINSON, AJ ;

FERSHT, AR ;

BLOW, DM ;

CARTER, P ;

WINTER, G .

NATURE, 1984, 307 (5947) :187-188

[30] MOLECULAR-BASIS FOR THE ACCUMULATION OF ACIDIC ISOZYMES OF TRIOSEPHOSPHATE ISOMERASE ON AGING [J].

YUAN, PM ;

TALENT, JM ;

GRACY, RW .

MECHANISMS OF AGEING AND DEVELOPMENT, 1981, 17 (02) :151-162

← 1 2 3 4 →