TRANSCRIPTIONAL REGULATION OF THE IL-2 GENE

被引：502

作者：

JAIN, J ^{[1
]}

LOH, C ^{[1
]}

RAO, A ^{[1
]}

机构：

[1] HARVARD UNIV,SCH MED,BOSTON,MA 02115

来源：

CURRENT OPINION IN IMMUNOLOGY | 1995年 / 7卷 / 03期

关键词：

D O I：

10.1016/0952-7915(95)80107-3

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The past two years have seen significant advances in our understanding of IL-2 gene transcription. Many of the relevant transcription factors have been identified, the intracellular mechanisms regulating their functions are being elucidated, and the multiple roles oi calcineurin are beginning to be appreciated.

引用

收藏

页码：333 / 342

页数：10

相关论文

共 112 条

[11] MOLECULAR-BASIS OF A MULTIPLE LYMPHOKINE DEFICIENCY IN A PATIENT WITH SEVERE COMBINED IMMUNODEFICIENCY [J].

CASTIGLI, E ;

PAHWA, R ;

GOOD, RA ;

GEHA, RS ;

CHATILA, TA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (10) :4728-4732

[12] INTERLEUKIN-2 TRANSCRIPTION FACTORS AS MOLECULAR TARGETS OF CAMP INHIBITION - DELAYED INHIBITION-KINETICS AND COMBINATORIAL TRANSCRIPTION ROLES [J].

CHEN, D ;

ROTHENBERG, EV .

JOURNAL OF EXPERIMENTAL MEDICINE, 1994, 179 (03) :931-942

[13] GENERATION OF NORMAL T-LYMPHOCYTES AND B-LYMPHOCYTES BY C-JUN DEFICIENT EMBRYONIC STEM-CELLS [J].

CHEN, JZ ;

STEWART, V ;

SPYROU, G ;

HILBERG, F ;

WAGNER, EF ;

ALT, FW .

IMMUNITY, 1994, 1 (01) :65-72

[14] JUN-B DIFFERS IN ITS BIOLOGICAL PROPERTIES FROM, AND IS A NEGATIVE REGULATOR OF, C-JUN [J].

CHIU, R ;

ANGEL, P ;

KARIN, M .

CELL, 1989, 59 (06) :979-986

[15] MULTIPLE CLOSELY-LINKED NFAT-OCTAMER AND HMG I(Y) BINDING-SITES ARE PART OF THE INTERLEUKIN-4 PROMOTER [J].

CHUVPILO, S ;

SCHOMBERG, C ;

GERWIG, R ;

HEINFLING, A ;

REEVES, R ;

GRUMMT, F ;

SERFLING, E .

NUCLEIC ACIDS RESEARCH, 1993, 21 (24) :5694-5704

[16]

CIVIL A, 1992, EUR J IMMUNOL, V22, P3401

[17] OCT-2 IS REQUIRED EARLY IN T-CELL-INDEPENDENT B-CELL ACTIVATION FOR G1 PROGRESSION AND FOR PROLIFERATION [J].

CORCORAN, LM ;

KARVELAS, M .

IMMUNITY, 1994, 1 (08) :635-645

[18] SIGNAL TRANSMISSION BETWEEN THE PLASMA-MEMBRANE AND NUCLEUS OF T-LYMPHOCYTES [J].

CRABTREE, GR ;

CLIPSTONE, NA .

ANNUAL REVIEW OF BIOCHEMISTRY, 1994, 63 :1045-1083

[19] MAPKS - NEW JNK EXPANDS THE GROUP [J].

DAVIS, RJ .

TRENDS IN BIOCHEMICAL SCIENCES, 1994, 19 (11) :470-473

[20] POSITIVE AND NEGATIVE REGULATION OF THE COMPOSITE OCTAMER MOTIF OF THE INTERLEUKIN-2 ENHANCER BY AP-1, OCT-2, AND RETINOIC ACID RECEPTOR [J].

DEGRAZIA, U ;

FELLI, MP ;

VACCA, A ;

FARINA, AR ;

MARODER, M ;

CAPPABIANCA, L ;

MECO, D ;

FARINA, M ;

SCREPANTI, I ;

FRATI, L ;

GULINO, A .

JOURNAL OF EXPERIMENTAL MEDICINE, 1994, 180 (04) :1485-1497

← 1 2 3 4 5 6 7 8 9 10 →