ONCOGENIC ACTIVATION OF THE NEU-ENCODED RECEPTOR PROTEIN BY POINT MUTATION AND DELETION

被引：326

作者：

BARGMANN, CI ^{[1
]}

WEINBERG, RA ^{[1
]}

机构：

[1] MIT,DEPT BIOL,CAMBRIDGE,MA 02142

来源：

EMBO JOURNAL | 1988年 / 7卷 / 07期

关键词：

D O I：

10.1002/j.1460-2075.1988.tb03044.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：2043 / 2052

页数：10

共 42 条

[31] CLONAL CELL LINES FROM RAT CENTRAL NERVOUS-SYSTEM [J].

SCHUBERT, D ;

HEINEMANN, S ;

CARLISLE, W ;

TARIKAS, H ;

KIMES, B ;

PATRICK, J ;

STEINBACH, JH ;

CULP, W ;

BRANDT, BL .

NATURE, 1974, 249 (5454) :224-227

[32] BIOLOGICAL PROPERTIES OF HUMAN C-HA-RAS 1 GENES MUTATED AT CODON-12 [J].

SEEBURG, PH ;

COLBY, WW ;

CAPON, DJ ;

GOEDDEL, DV ;

LEVINSON, AD .

NATURE, 1984, 312 (5989) :71-75

[33] THE C-FMS PROTO-ONCOGENE PRODUCT IS RELATED TO THE RECEPTOR FOR THE MONONUCLEAR PHAGOCYTE GROWTH-FACTOR, CSF-1 [J].

SHERR, CJ ;

RETTENMIER, CW ;

SACCA, R ;

ROUSSEL, MF ;

LOOK, AT ;

STANLEY, ER .

CELL, 1985, 41 (03) :665-676

[34] TRANSFORMING GENES OF CARCINOMAS AND NEUROBLASTOMAS INTRODUCED INTO MOUSE FIBROBLASTS [J].

SHIH, C ;

PADHY, LC ;

MURRAY, M ;

WEINBERG, RA .

NATURE, 1981, 290 (5803) :261-264

[35] HUMAN-BREAST CANCER - CORRELATION OF RELAPSE AND SURVIVAL WITH AMPLIFICATION OF THE HER-2 NEU ONCOGENE [J].

SLAMON, DJ ;

CLARK, GM ;

WONG, SG ;

LEVIN, WJ ;

ULLRICH, A ;

MCGUIRE, WL .

SCIENCE, 1987, 235 (4785) :177-182

[36]

SOUTHERN P J, 1982, Journal of Molecular and Applied Genetics, V1, P327

[37] P185, A PRODUCT OF THE NEU PROTOONCOGENE, IS A RECEPTOR-LIKE PROTEIN ASSOCIATED WITH TYROSINE KINASE-ACTIVITY [J].

STERN, DF ;

HEFFERNAN, PA ;

WEINBERG, RA .

MOLECULAR AND CELLULAR BIOLOGY, 1986, 6 (05) :1729-1740

[38] THE PRODUCT OF RAS IS A GTPASE AND THE T24 ONCOGENIC MUTANT IS DEFICIENT IN THIS ACTIVITY [J].

SWEET, RW ;

YOKOYAMA, S ;

KAMATA, T ;

FERAMISCO, JR ;

ROSENBERG, M ;

GROSS, M .

NATURE, 1984, 311 (5983) :273-275

[39] HUMAN EPIDERMAL GROWTH-FACTOR RECEPTOR CDNA SEQUENCE AND ABERRANT EXPRESSION OF THE AMPLIFIED GENE IN A431 EPIDERMOID CARCINOMA-CELLS [J].

ULLRICH, A ;

COUSSENS, L ;

HAYFLICK, JS ;

DULL, TJ ;

GRAY, A ;

TAM, AW ;

LEE, J ;

YARDEN, Y ;

LIBERMANN, TA ;

SCHLESSINGER, J ;

DOWNWARD, J ;

MAYES, ELV ;

WHITTLE, N ;

WATERFIELD, MD ;

SEEBURG, PH .

NATURE, 1984, 309 (5967) :418-425

[40]

VARMUS HE, 1984, ANNU REV GENET, V18, P553

← 1 2 3 4 5 →