SELECTIVE INACTIVATION OF VITAMIN-B12 IN RATS BY NITROUS-OXIDE

被引:182
作者
DEACON, R [1 ]
LUMB, M [1 ]
CHANARIN, I [1 ]
PERRY, J [1 ]
MINTY, B [1 ]
HALSEY, MJ [1 ]
NUNN, JF [1 ]
机构
[1] NORTHWICK PK HOSP, CLIN RES CTR, DIV ANAESTHESIA, HARROW HA1 3UJ, MIDDLESEX, ENGLAND
关键词
D O I
10.1016/S0140-6736(78)92341-3
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Exposure of rats to nitrous oxide rapidly inactivated the cytosol enzyme, methionine synthetase, but the mitochondrial enzyme, methylmalonyl CoA mutase, seemed to be unaffected, although both enzymes require vitamin B12. © 1978.
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页码:1023 / 1024
页数:2
相关论文
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