EFFECT OF VITAMIN-B12 INHIBITION INVIVO - IMPAIRED FOLATE POLYGLUTAMATE BIOSYNTHESIS INDICATING THAT "5-METHYLTETRAHYDROPTEROYL-GLUTAMATE IS NOT ITS USUAL SUBSTRATE

被引：48

作者：

MCGING, P ^{[1
]}

REED, B ^{[1
]}

WEIR, DG ^{[1
]}

SCOTT, JM ^{[1
]}

机构：

[1] UNIV DUBLIN,TRINITY COLL,DEPT MED,DUBLIN,IRELAND

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1978年 / 82卷 / 02期

关键词：

D O I：

10.1016/0006-291X(78)90908-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：540 / 546

页数：7

共 16 条

[1]

AMESS JAL, 1977, INT SOC HAEMATOL IST, P614

[2] IDENTIFICATION OF HEXAGLUTAMATES, HEPTAGLUTAMATES AND OCTAGLUTAMATES AS POLYGLUTAMYL FORMS OF FOLATE FOUND THROUGHOUT GROWTH-CYCLE OF YEAST [J].

BASSETT, R ;

WEIR, DG ;

SCOTT, JM .

JOURNAL OF GENERAL MICROBIOLOGY, 1976, 93 (MAR) :169-172

[3] REACTION OF COB(I)ALAMIN WITH NITROUS-OXIDE AND COB(III)ALAMIN [J].

BLACKBURN, R ;

KYAW, M ;

SWALLOW, AJ .

JOURNAL OF THE CHEMICAL SOCIETY-FARADAY TRANSACTIONS I, 1977, 73 :250-255

[4] SPECIFICITY OF FOLIATE-GAMMA-L-GLUTAMATE LIGASE IN RAT-LIVER AND KIDNEY - BIOSYNTHESIS OF POLY-GAMMA-L-GLUTAMATES OF UNREDUCED METHOTREXATE AND EFFECT OF METHOTREXATE ON FOLATE POLYGLUTAMATE BIOSYNTHESIS [J].

BROWN, JP ;

DAVIDSON, GE ;

WEIR, DG ;

SCOTT, JM .

INTERNATIONAL JOURNAL OF BIOCHEMISTRY, 1974, 5 (9-10) :727-733

[5] IDENTIFICATION OF FORMS OF FOLATE FOUND IN LIVER, KIDNEY AND INTESTINE OF MONKEY AND THEIR BIOSYNTHESIS FROM EXOGENOUS PTEROYLGLUTAMATE (FOLIC-ACID) [J].

BROWN, JP ;

DAVIDSON, GE ;

SCOTT, JM .

BIOCHIMICA ET BIOPHYSICA ACTA, 1974, 343 (01) :78-88

[6] THIN-LAYER CHROMATOGRAPHY OF PTEROYLGLUTAMATES AND RELATED COMPOUNDS - APPLICATION TO TRANSPORT AND METABOLISM OF REDUCED FOLATES IN BLOOD [J].

BROWN, JP ;

DAVIDSON, GE ;

SCOTT, JM .

JOURNAL OF CHROMATOGRAPHY, 1973, 79 (MAY16) :195-207

[7]

CHANARIN I, 1974, LANCET, V1, P1251

[8] METABOLIC CONSEQUENCES OF VITAMIN-B-12 METHIONINE DEFICIENCY IN RATS [J].

DAVIDSON, GE ;

WEIR, DG ;

SCOTT, JM .

BIOCHIMICA ET BIOPHYSICA ACTA, 1975, 392 (02) :207-215

[9] IDENTIFICATION OF PTEROYLPENTAGLUTAMATE AS MAJOR FOLATE DERIVATIVE IN RAT-LIVER AND DEMONSTRATION OF ITS BIOSYNTHESIS FROM EXOGENOUS [H-3] PTEROYLGLUTAMATE [J].

HOULIHAN, CM ;

SCOTT, JM .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1972, 48 (06) :1675-&

[10]

KRIPKE BJ, 1977, ANESTHESIOLOGY, V47, P342

← 1 2 →