HORMONAL-REGULATION OF PEPTIDE RECEPTORS AND TARGET-CELL RESPONSES

被引：595

作者：

CATT, KJ

HARWOOD, JP

AGUILERA, G

DUFAU, ML

机构：

[1] Endocrinology and Reproduction Research Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda

来源：

NATURE | 1979年 / 280卷 / 5718期

关键词：

D O I：

10.1038/280109a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Regulation of plasma membrane receptors for peptide hormones by the prevailing ligand concentration often causes altered target cell function. Receptor number is determined by hormone-induced changes in membrane conformation, irreversible ligand binding, and processing of ligand-receptor complexes during hormone action. © 1979 Nature Publishing Group.

引用

页码：109 / 116

页数：8

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