CHARACTERIZATION OF THE BINDING OF N-METHYL-4-PHENYLPYRIDINE, THE TOXIC METABOLITE OF THE PARKINSONIAN NEUROTOXIN N-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE, TO NEUROMELANIN

被引：42

作者：

DAMATO, RJ

BENHAM, DF

SNYDER, SH

机构：

[1] JOHNS HOPKINS UNIV,SCH MED,DEPT NEUROSCI,725 N WOLFE ST,BALTIMORE,MD 21205

[2] JOHNS HOPKINS UNIV,SCH MED,DEPT PHARMACOL & EXPTL THERAPEUT,BALTIMORE,MD 21205

[3] JOHNS HOPKINS UNIV,SCH MED,DEPT PSYCHIAT,BALTIMORE,MD 21205

[4] JOHNS HOPKINS UNIV,SCH MED,DEPT BEHAV SCI,BALTIMORE,MD 21205

来源：

JOURNAL OF NEUROCHEMISTRY | 1987年 / 48卷 / 02期

关键词：

D O I：

10.1111/j.1471-4159.1987.tb04142.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：653 / 658

页数：6

共 28 条

[1] COMPARATIVE MOSSBAUER AND INFRARED-ANALYSIS OF IRON-CONTAINING MELANINS [J].

BARDANI, L ;

BRIDELLI, MG ;

CARBUCICCHIO, M ;

CRIPPA, PR .

BIOCHIMICA ET BIOPHYSICA ACTA, 1982, 716 (01) :8-15

[2] INCORPORATION OF VARIOUS METAL IONS INTO IN VIVO- AND IN VITRO-PRODUCED MELANIN [J].

BRUENGER, FW ;

STOVER, BJ ;

ATHERTON, DR .

RADIATION RESEARCH, 1967, 32 (01) :1-&

[3] A PRIMATE MODEL OF PARKINSONISM - SELECTIVE DESTRUCTION OF DOPAMINERGIC-NEURONS IN THE PARS COMPACTA OF THE SUBSTANTIA NIGRA BY N-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE [J].

BURNS, RS ;

CHIUEH, CC ;

MARKEY, SP ;

EBERT, MH ;

JACOBOWITZ, DM ;

KOPIN, IJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (14) :4546-4550

[4] METABOLISM OF THE NEUROTOXIC TERTIARY AMINE, MPTP, BY BRAIN MONOAMINE-OXIDASE [J].

CHIBA, K ;

TREVOR, A ;

CASTAGNOLI, N .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1984, 120 (02) :574-578

[5] SELECTIVITY OF THE PARKINSONIAN NEUROTOXIN MPTP - TOXIC METABOLITE MPP+ BINDS TO NEUROMELANIN [J].

DAMATO, RJ ;

LIPMAN, ZP ;

SNYDER, SH .

SCIENCE, 1986, 231 (4741) :987-989

[6] NEURONAL PIGMENTS - SPECTROSCOPIC CHARACTERIZATION OF HUMAN-BRAIN MELANIN [J].

DAS, KC ;

ABRAMSON, MB ;

KATZMAN, R .

JOURNAL OF NEUROCHEMISTRY, 1978, 30 (03) :601-606

[7] CHRONIC PARKINSONISM SECONDARY TO INTRAVENOUS-INJECTION OF MEPERIDINE ANALOGS [J].

DAVIS, GC ;

WILLIAMS, AC ;

MARKEY, SP ;

EBERT, MH ;

CAINE, ED ;

REICHERT, CM ;

KOPIN, IJ .

PSYCHIATRY RESEARCH, 1979, 1 (03) :249-254

[8] CALCIUM-BINDING IN PIGMENTED AND ALBINO EYES [J].

DRAGER, UC .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (19) :6716-6720

[9] INFLUENCE OF SELECTIVE, REVERSIBLE INHIBITORS OF MONOAMINE-OXIDASE ON THE PROLONGED DEPLETION OF STRIATAL DOPAMINE BY 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE IN MICE [J].

FULLER, RW ;

HEMRICKLUECKE, SK .

LIFE SCIENCES, 1985, 37 (12) :1089-1096

[10] NEUROCHEMICAL AND HISTOCHEMICAL CHARACTERIZATION OF NEUROTOXIC EFFECTS OF 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE ON BRAIN CATECHOLAMINE NEURONS IN THE MOUSE [J].

HALLMAN, H ;

LANGE, J ;

OLSON, L ;

STROMBERG, I ;

JONSSON, G .

JOURNAL OF NEUROCHEMISTRY, 1985, 44 (01) :117-127

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