MULTIPLE MOLECULAR SPECIES OF CIRCULAR R-FACTOR DNA ISOLATED FROM ESCHERICHIA-COLI

被引：90

作者：

COHEN, SN

MILLER, CA

机构：

[1] Department of Medicine, Stanford University, School of Medicine, Stanford

来源：

NATURE | 1969年 / 224卷 / 5226期

关键词：

D O I：

10.1038/2241273a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Using a rapid one-step method, circular DNA has been isolated from a strain of E. coli harbouring the R-factor R-1 and shown to contain at least two separate classes of covalently closed molecules. Evidence is presented for the stable existence of circular R-factor in E. coli. © 1969 Nature Publishing Group.

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页码：1273 / &

相关论文

共 25 条

[1] CHARACTERIZATION OF A TRANSFER FACTOR ASSOCIATED WITH DRUG RESISTANCE IN SALMONELLA TYPHIMURIUM [J].

ANDERSON, ES ;

LEWIS, MJ .

NATURE, 1965, 208 (5013) :843-&

[2] ECOLOGY OF TRANSFERABLE DRUG RESISTANCE IN ENTEROBACTERIA [J].

ANDERSON, ES .

ANNUAL REVIEW OF MICROBIOLOGY, 1968, 22 :131-&

[3] CIRCULAR DNA FORMS OF COLICINOGENIC FACTORS E1 E2 AND E3 FROM ESCHERICHIA COLI [J].

BAZARAL, M ;

HELINSKI, DR .

JOURNAL OF MOLECULAR BIOLOGY, 1968, 36 (02) :185-&

[4] CHARACTERIZATION OF MULTIPLE CIRCULAR DNA FORMS OF COLINCINOGENIC FACTOR E1 FROM PROTEUS MIRABILIS [J].

BAZARAL, M ;

HELINSKI, DR .

BIOCHEMISTRY, 1968, 7 (10) :3513-&

[5] CHANGES IN MOLECULAR WEIGHT OF DNA ACCOMPANYING MUTATIONS IN PHAGE [J].

BURGI, E .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1963, 49 (02) :151-&

[6]

COHEN S N, 1969, Bacteriological Proceedings, V69, P49

[7] GENETIC TRANSCRIPTION IN BACTERIOPHAGE LAMBDA -LSTUDIES OF LAMBDA MRNA SYNTHESIS IN VIVO [J].

COHEN, SN ;

HURWITZ, J .

JOURNAL OF MOLECULAR BIOLOGY, 1968, 37 (03) :387-&

[8] ISOLATION OF DNA OF E COLI CHROMOSOME IN 1 PIECE [J].

DAVERN, CI .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1966, 55 (04) :792-&

[9]

EIGNER J, 1968, METHODS ENZYMOLOGY B, V12, P386

[10] MOLECULAR NATURE OF R-FACTORS [J].

FALKOW, S ;

CITARELL.RV ;

WOHLHIET.JA ;

WATANABE, T .

JOURNAL OF MOLECULAR BIOLOGY, 1966, 17 (01) :102-&