POLYS LAMENT - THE NEGLECTED ROLE OF THE POLYMORPHONUCLEAR NEUTROPHIL IN THE AFFERENT LIMB OF THE IMMUNE-RESPONSE

被引：403

作者：

LLOYD, AR

OPPENHEIM, JJ

机构：

[1] Laboratory of Molecular Immunoregulation, National Cancer Institute, Frederick

来源：

IMMUNOLOGY TODAY | 1992年 / 13卷 / 05期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/0167-5699(92)90121-M

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The polymorphonuclear leucocyte (PMN) has traditionally been thought to participate in the inflammatory response only as an effector cell. However, recent data demonstrate that PMNs can synthesize and release cytokines, such as IL-1, TNF-alpha and IL-6, and hence modulate both T- and B-cell activities in the evolution of an immune response.

引用

页码：169 / 172

页数：4

共 38 条

[1] DEVELOPMENT OF NEUTROPHILIC POLYMORPHONUCLEAR LEUKOCYTES IN HUMAN BONE MARROW - ORIGIN AND CONTENT OF AZUROPHIL AND SPECIFIC GRANULES [J].