PASSIVE-AVOIDANCE LEARNING IN LESCH-NYHAN DISEASE - EFFECT OF 1-DESAMINO-8-ARGININE-VASOPRESSIN

被引：38

作者：

ANDERSON, LT ^{[1
]}

DAVID, R ^{[1
]}

BONNET, K ^{[1
]}

DANCIS, J ^{[1
]}

机构：

[1] NYU,BELLEVUE MED CTR,DEPT PEDIAT,NEW YORK,NY 10016

来源：

LIFE SCIENCES | 1979年 / 24卷 / 10期

关键词：

D O I：

10.1016/0024-3205(79)90340-0

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Previous studies have shown that self-mutilation can be controlled in Lesch-Nyhan children by operant conditioning. Punishment was unsuccessful as a teaching modality. A passive avoidance learning defect has now been confirmed under controlled experimental conditions in 3 children with Lesch-Nyhan disease. The ability to learn was repeatedly and consistently improved in these children by the administration of a vasopressin analogue prior to testing. © 1979.

引用

页码：905 / 910

页数：6

共 13 条

[1] PUNISHMENT LEARNING AND SELF-MUTILATION IN LESCH-NYHAN DISEASE [J].