GENETIC ABLATION - TARGETED EXPRESSION OF A TOXIN GENE CAUSES MICROPHTHALMIA IN TRANSGENIC MICE

被引：196

作者：

BREITMAN, ML

CLAPOFF, S

ROSSANT, J

TSUI, LC

GLODE, LM

MAXWELL, IH

BERNSTEIN, A

机构：

[1] UNIV TORONTO,DEPT MED GENET,TORONTO M5S 1A8,ONTARIO,CANADA

[2] HOSP SICK CHILDREN,DEPT GENET,TORONTO M5G 1X8,ONTARIO,CANADA

[3] UNIV COLORADO,HLTH SCI CTR,DIV MED ONCOL,DENVER,CO 80262

来源：

SCIENCE | 1987年 / 238卷 / 4833期

关键词：

D O I：

10.1126/science.3685993

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：1563 / 1565

页数：3

共 24 条

[1] INTRODUCTION OF A SELECTABLE GENE INTO PRIMITIVE STEM-CELLS CAPABLE OF LONG-TERM RECONSTITUTION OF THE HEMATOPOIETIC SYSTEM OF W/WV MICE [J].

DICK, JE ;

MAGLI, MC ;

HUSZAR, D ;

PHILLIPS, RA ;

BERNSTEIN, A .

CELL, 1985, 42 (01) :71-79

[2] A TECHNIQUE FOR RADIOLABELING DNA RESTRICTION ENDONUCLEASE FRAGMENTS TO HIGH SPECIFIC ACTIVITY [J].

FEINBERG, AP ;

VOGELSTEIN, B .

ANALYTICAL BIOCHEMISTRY, 1983, 132 (01) :6-13

[3] THE HOMEO BOX - A KEY TO THE UNDERSTANDING OF DEVELOPMENT [J].

GEHRING, WJ .

CELL, 1985, 40 (01) :3-5

[4] INSITU DETECTION OF BETA-GALACTOSIDASE IN LENSES OF TRANSGENIC MICE WITH A GAMMA-CRYSTALLIN-LACZ GENE [J].

GORING, DR ;

ROSSANT, J ;

CLAPOFF, S ;

BREITMAN, ML ;

TSUI, LC .

SCIENCE, 1987, 235 (4787) :456-458

[5] EXPRESSION OF A FOREIGN GENE IN MYELOID AND LYMPHOID-CELLS DERIVED FROM MULTIPOTENT HEMATOPOIETIC PRECURSORS [J].

KELLER, G ;

PAIGE, C ;

GILBOA, E ;

WAGNER, EF .

NATURE, 1985, 318 (6042) :149-154

[6] ALTERATIONS IN CELL LINEAGE FOLLOWING LASER ABLATION OF CELLS IN THE SOMATIC GONAD OF CAENORHABDITIS-ELEGANS [J].

KIMBLE, J .

DEVELOPMENTAL BIOLOGY, 1981, 87 (02) :286-300

[7] DEVELOPMENTAL POTENTIAL AND DYNAMIC BEHAVIOR OF HEMATOPOIETIC STEM-CELLS [J].

LEMISCHKA, IR ;

RAULET, DH ;

MULLIGAN, RC .

CELL, 1986, 45 (06) :917-927

[8]

LO CW, 1986, J CELL SCI, V81, P143

[9] LENS-SPECIFIC PROMOTER ACTIVITY OF A MOUSE GAMMA-CRYSTALLIN GENE [J].

LOK, S ;

BREITMAN, ML ;

CHEPELINSKY, AB ;

PIATIGORSKY, J ;

GOLD, RJM ;

TSUI, LC .

MOLECULAR AND CELLULAR BIOLOGY, 1985, 5 (09) :2221-2230

[10]

MAXWELL IH, 1986, CANCER RES, V46, P4660

← 1 2 3 →