AUTORADIOGRAPHIC LOCALIZATION OF NMDA, QUISQUALATE AND KAINIC ACID RECEPTORS IN HUMAN SPINAL-CORD

被引：86

作者：

JANSEN, KLR

FAULL, RLM

DRAGUNOW, M

WALDVOGEL, H

机构：

[1] Department of Anatomy, University of Auckland, School of Medicine, Auckland

来源：

NEUROSCIENCE LETTERS | 1990年 / 108卷 / 1-2期

基金：

英国医学研究理事会;

关键词：

Autoradiography; Human; Kainic acid receptor; N-Methyl-d-aspartate receptor; Phencyclidine; Quisqualate receptor; Spinal cord;

D O I：

10.1016/0304-3940(90)90705-E

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The phencyclidine (PCP) binding site of the N-methyl-d-aspartate receptor, the kainic acid (KA) receptor and the quisqualate (QA) receptor were visualised, using autoradiography in the human spinal cord and the distributions compared with that of benzodiazepine (BDZ) receptors and substance P (SP). All of the receptor types, and SP, were concentrated in lamina II of the dorsal horn, consistent with physiological data indicating that glutamate is a neurotransmitter of primary afferent terminals in the spinal cord. © 1990.

引用

页码：53 / 57

页数：5

共 21 条

[1] GABAERGIC TERMINALS ARE PRESYNAPTIC TO PRIMARY AFFERENT TERMINALS IN SUBSTANTIA GELATINOSA OF RAT SPINAL-CORD [J].