PICROTOXIN ANTAGONISM OF INHIBITION OF INTERNEURONS BY GLYCINE

被引：30

作者：

DAVIDOFF, RA

APRISON, MH

机构：

[1] The Veterans Administration Hospital, the Institute of Psychiatric Research Indiana University Medical Center, Indianapolis, IN

[2] Departments of Psychiatry, Neurology and Biochemistry, Indiana University Medical Center, Indianapolis, IN

来源：

LIFE SCIENCES PART 1 PHYSIOLOGY AND PHARMACOLOGY AND PART 2 BIOCHEMISTRY GENERAL AND MOLECULAR BIOLOGY | 1969年 / 8卷 / 1P1期

关键词：

D O I：

10.1016/0024-3205(69)90299-9

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

By means of 5-barrel micropipettes, it was shown that the inhibitory effects of iontophoresed glycine on spinal interneurons was antagonized by the iontophoresis of picrotoxin. The blocking effects of picrotoxin were shown to be pH dependent. The possible role of glycine as a transmitter involved in picrotoxin-sensitive spinal inhibition was raised. © 1969.

引用

页码：107 / &

共 19 条

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