T-CELL CO-RECEPTORS - THE END OF A FRUSTRATING SEARCH

被引：5

作者：

BENOIST, C ^{[1
]}

MATHIS, D ^{[1
]}

机构：

[1] INST CHIM BIOL,INSERM,UNITE BIOL MOLEC 184,F-67085 STRASBOURG,FRANCE

来源：

CURRENT BIOLOGY | 1994年 / 4卷 / 09期

关键词：

D O I：

10.1016/S0960-9822(00)00182-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The identification of a 'silencer' element that turns off CD4 gene expression at specific stages in thymocyte differentiation may help to resolve an important outstanding problem in immunology.

引用

页码：821 / 823

页数：3

共 13 条

[1] RECONSTITUTION OF THE SUBCLASS-SPECIFIC EXPRESSION OF CD4 IN THYMOCYTES AND PERIPHERAL T-CELLS OF TRANSGENIC MICE - IDENTIFICATION OF A HUMAN CD4 ENHANCER [J].

BLUM, MD ;

WONG, GT ;

HIGGINS, KM ;

SUNSHINE, MJ ;

LACY, E .

JOURNAL OF EXPERIMENTAL MEDICINE, 1993, 177 (05) :1343-1358

[2] TOWARDS AN INTEGRATED VIEW OF THYMOPOIESIS [J].

BOYD, RL ;

HUGO, P .

IMMUNOLOGY TODAY, 1991, 12 (02) :71-+

[3] CHARACTERIZATION OF A SILENCER IN YEAST - A DNA-SEQUENCE WITH PROPERTIES OPPOSITE TO THOSE OF A TRANSCRIPTIONAL ENHANCER [J].

BRAND, AH ;

BREEDEN, L ;

ABRAHAM, J ;

STERNGLANZ, R ;

NASMYTH, K .

CELL, 1985, 41 (01) :41-48

[4] A CHALLENGE TO THE INSTRUCTIVE MODEL OF POSITIVE SELECTION [J].

CHAN, SH ;

BENOIST, C ;

MATHIS, D .

IMMUNOLOGICAL REVIEWS, 1993, 135 :119-131

[5] TISSUE-SPECIFIC EXPRESSION OF HUMAN CD4 IN TRANSGENIC MICE [J].

GILLESPIE, FP ;

DOROS, L ;

VITALE, J ;

BLACKWELL, C ;

GOSSELIN, J ;

SNYDER, BW ;

WADSWORTH, SC .

MOLECULAR AND CELLULAR BIOLOGY, 1993, 13 (05) :2952-2958

[6] SPECIFIC EXPRESSION OF THE HUMAN CD4 GENE IN MATURE CD4+ CD8- AND IMMATURE CD4+ CD8+ T-CELLS AND IN MACROPHAGES OF TRANSGENIC MICE [J].

HANNA, Z ;

SIMARD, C ;

LAPERRIERE, A ;

JOLICOEUR, P .

MOLECULAR AND CELLULAR BIOLOGY, 1994, 14 (02) :1084-1094

[7] REGULATED EXPRESSION OF HUMAN CD4 RESCUES HELPER T-CELL DEVELOPMENT IN MICE LACKING EXPRESSION OF ENDOGENOUS CD4 [J].

KILLEEN, N ;

SAWADA, S ;

LITTMAN, DR .

EMBO JOURNAL, 1993, 12 (04) :1547-1553

[8] CHARACTERIZATION OF THE HUMAN CD4 GENE PROMOTER - TRANSCRIPTION FROM THE CD4 GENE CORE PROMOTER IS TISSUE-SPECIFIC AND IS ACTIVATED BY ETS PROTEINS [J].

SALMON, P ;

GIOVANE, A ;

WASYLYK, B ;

KLATZMANN, D .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (16) :7739-7743

[9] T-CELL-SPECIFIC PROTEIN-DNA INTERACTIONS OCCURRING AT THE CD4 LOCUS - IDENTIFICATION OF POSSIBLE TRANSCRIPTIONAL CONTROL ELEMENTS OF THE MURINE CD4 GENE [J].

SANDS, JF ;

NIKOLICZUGIC, J .

INTERNATIONAL IMMUNOLOGY, 1992, 4 (10) :1183-1194

[10] IDENTIFICATION AND CHARACTERIZATION OF A T-CELL-SPECIFIC ENHANCER ADJACENT TO THE MURINE CD4 GENE [J].

SAWADA, S ;

LITTMAN, DR .

MOLECULAR AND CELLULAR BIOLOGY, 1991, 11 (11) :5506-5515

← 1 2 →