ASCORBIC ACID - COFACTOR IN RABBIT OLFACTORY PREPARATIONS

被引：23

作者：

ASH, KO

机构：

[1] Honeywell Corporate Research Center, Hopkins, MN 55343

来源：

SCIENCE | 1969年 / 165卷 / 3896期

关键词：

D O I：

10.1126/science.165.3896.901

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A stimulant-induced decrease in absorbance at 267 nanometers in preparations from rabbit olfactory epithelium requires ascorbic acid as a cofactor. Vitamin C is bound to proteins in the olfactory mucosa in vivo. When the stimulant 3,7-dimethyl-6-octen-3-ol interacts with olfactory proteins, it triggers a change in protein conformation which renders ascorbic acid available for oxidation. The specific decrease in absorbance at 267 nanometers is produced when the freed" ascorbic acid is oxidized."

引用

页码：901 / &

共 14 条

[1] CHEMICAL SENSING - AN APPROACH TO BIOLOGICAL MOLECULAR MECHANISMS USING DIFFERENCE SPECTROSCOPY [J].