共 2 条
DETERMINATION OF ASPIRIN, SALICYLIC-ACID, SALICYLURIC ACID, AND GENTISIC ACID IN HUMAN-PLASMA AND URINE BY HIGH-PRESSURE LIQUID-CHROMATOGRAPHY
被引:54
作者:
AMICK, EN
[1
]
MASON, WD
[1
]
机构:
[1] UNIV MISSOURI,SCH MED,KANSAS CITY,MO 64108
关键词:
D O I:
10.1080/00032717908055714
中图分类号:
O65 [分析化学];
学科分类号:
070302 ;
081704 ;
摘要:
A method has been developed to simultaneously determine aspirin, salicylic acid, salicyluric acid, and gentisic acid concentrations in human plasma and urine. An extraction and dry-down step prepare the sample for resolution by reverse-phase high pressure liquid chromatography. The column effluent is monitored by both ultraviolet absorbance and fluorescence to optimize sensitivity and specificity for the compounds of interest. © 1979, Taylor & Francis Group, LLC. All rights reserved.
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页码:629 / 640
页数:12
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