ESTROGEN-BINDING SITES IN ENDOTHELIAL CELL-CULTURES

被引：233

作者：

COLBURN, P

BUONASSISI, V

机构：

[1] Department of Biology, C-016, University of California at San Diego, San Diego

来源：

SCIENCE | 1978年 / 201卷 / 4358期

关键词：

D O I：

10.1126/science.684408

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The cytosol extracted from a vascular endothelial cell line binds [ 3H]estradiol with high affinity and a high degree of specificity. In contrast, in experiments performed with cytosol labeled in the intact cell, progesterone and, to a smaller extent, testosterone gave an apparent inhibition of estradiol binding. These data support the concept that ovarian hormones may influence the role of the endothelium in various physiological and pathophysiological conditions. Copyright © 1978 AAAS.

引用

页码：817 / 819

页数：3

共 7 条

[1] HORMONE AND NEUROTRANSMITER RECEPTORS IN AN ESTABLISHED VASCULAR ENDOTHELIAL CELL LINE [J].