IMMUNOHISTOCHEMICAL DIFFERENTIAL-DIAGNOSIS OF GRANULOCYTIC SARCOMAS AND MALIGNANT-LYMPHOMAS ON FORMALIN-FIXED MATERIAL

被引：26

作者：

FELLBAUM, C ^{[1
]}

HANSMANN, ML ^{[1
]}

机构：

[1] UNIV KIEL,INST PATHOL,LYMPH NODE REGISTRY,MICHAELISSTR 11,W-2300 KIEL 1,GERMANY

来源：

VIRCHOWS ARCHIV A-PATHOLOGICAL ANATOMY AND HISTOPATHOLOGY | 1990年 / 416卷 / 04期

关键词：

Granulocytic sarcoma; Immunohistochemistry; Malignant lymphoma; Naphthol ASD chloroacetate reaction; Nasal region;

D O I：

10.1007/BF01605296

中图分类号：

R602 [外科病理学、解剖学]; R32 [人体形态学];

学科分类号：

100101 ;

摘要：

A panel of monoclonal antibodies (anti-CD45 [common leukocyte antigen], Ki-B3, L26, MT1, UCHL1, anti-CD15 [X-hapten], anti-neutrophil granule protein elastase [NP57]), anti-lysozyme, and the naphthol-ASD-chloroacetate reaction were applied to two cases of granulocytic sarcoma (GS) for evaluation of their utility in differentiating GS from malignant lymphoma. Lysozyme and naphthol-ASD-chloroacetate esterase were found to be the most reliable markers for detection of the myeloid nature of the tumour cells. GS infiltrated solely the mucosa of the nasal cavity in one case, while in the other it involved both the nasal cavity and maxillary sinus with simultaneous eruptions on the skin of the trunk. In both cases, peripheral blood and bone marrow findings were inconspicuous at the time of diagnosis of GS. © 1990 Springer-Verlag.

引用

页码：351 / 355

页数：5

共 29 条

[1] GRANULOCYTIC SARCOMA OF THE HARD PALATE - REPORT OF THE 1ST CASE [J].

CASTELLA, A ;

DAVEY, FR ;

ELBADAWI, A ;

GORDON, GB .

HUMAN PATHOLOGY, 1984, 15 (12) :1190-1192

[2] DIAGNOSIS OF GRANULOCYTIC SARCOMA [J].

CHAN, JKC ;

NG, CS .

PATHOLOGY, 1987, 19 (03) :317-317

[3] THE IMMUNOPHENOTYPING OF EXTRAMEDULLARY MYELOID CELL TUMORS IN PARAFFIN-EMBEDDED TISSUE-SECTIONS [J].

DAVEY, FR ;

OLSON, S ;

KUREC, AS ;

EASTMANABAYA, R ;

GOTTLIEB, AJ ;

MASON, DY .

AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1988, 12 (09) :699-707

[4] MALIGNANT-LYMPHOMAS OF THE NASAL CAVITY AND PARA-NASAL SINUSES [J].

FELLBAUM, C ;

HANSMANN, ML ;

LENNERT, K .

VIRCHOWS ARCHIV A-PATHOLOGICAL ANATOMY AND HISTOPATHOLOGY, 1989, 414 (05) :399-405

[5]

FELLER AC, 1987, BLOOD, V70, P629

[6] PARAFFIN SECTION IMMUNOHISTOCHEMISTRY .1. NON-HODGKINS LYMPHOMA [J].

HALL, PA ;

DARDENNE, AJ ;

STANSFELD, AG .

HISTOPATHOLOGY, 1988, 13 (02) :149-160

[7] PARAGRANULOMA IS A VARIANT OF HODGKINS-DISEASE WITH PREDOMINANCE OF B-CELLS [J].

HANSMANN, ML ;

WACKER, HH ;

RADZUN, HJ .

VIRCHOWS ARCHIV A-PATHOLOGICAL ANATOMY AND HISTOPATHOLOGY, 1986, 409 (02) :171-181

[8]

KRAUSE JR, 1979, CANCER-AM CANCER SOC, V44, P1017, DOI 10.1002/1097-0142(197909)44:3<1017::AID-CNCR2820440333>3.0.CO

[9]

2-I

[10] LEUKOCYTE COMMON ANTIGEN - A DIAGNOSTIC DISCRIMINANT BETWEEN HEMATOPOIETIC AND NONHEMATOPOIETIC NEOPLASMS IN PARAFFIN SECTIONS USING MONOCLONAL-ANTIBODIES - CORRELATION WITH IMMUNOLOGICAL STUDIES AND ULTRASTRUCTURAL-LOCALIZATION [J].

KURTIN, PJ ;

PINKUS, GS .

HUMAN PATHOLOGY, 1985, 16 (04) :353-365

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