INTERSPECIES COMPARISON OF CARCINOGENIC POTENCY

被引：105

作者：

CROUCH, E

WILSON, R

机构：

[1] Energy and Environmental Policy Center, Jefferson Physics Laboratory, Harvard University, Cambridge, MA

来源：

JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH | 1979年 / 5卷 / 06期

关键词：

D O I：

10.1080/15287397909529817

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

For guidance in decisions on how to safeguard humans from carcinogens, it is necessary to use data on carcinogenesis in animals. This paper discusses how such data, combined with human experience, may be used quantitatively in such decisions, it is demonstrated empirically that good correlations exist between different species for suitably defined carcinogenic potencies for various chemicals. This allows sufficient accuracy in extrapolating from animal data to human risk to support a logical scheme for the evaluation of such risks. Some recommendations for future research are given. © 1979 Taylor & Francis Group, LLC.

引用

页码：1095 / 1118

页数：24

共 53 条

[1]

ALBERT RE, 1977, CARCINOGENESIS ASSES

[2]

[Anonymous], 1975, QUANTITATIVE RISK AS

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