NUCLEAR MAGNETIC RESONANCE STUDIES OF SOME BIOLOGICALLY ACTIVE DIHYDROPTERINS

被引：52

作者：

FUKUSHIM.T

AKINO, M

机构：

[1] Department of Biology, Faculty of Science, Tokyo Metropolitan University, Setagaya-ku, Tokyo

来源：

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS | 1968年 / 128卷 / 01期

关键词：

D O I：

10.1016/0003-9861(68)90002-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

An improved isolation method for biopterin and neopterin from natural sources is described. Crystalline dihydrobiopterin and dihydroneopterin were prepared by reduction with sodium dithionite and successive purification by column chromatography. The 7,8-dihydro structure of dihydrobiopterin and dihydroneopterin was established by comparing their nuclear magnetic resonance (NMR) spectra to those of authentic 7,8-dihydropteridines. The NMR spectrum of sepiapterin revealed that this compound also has the 7,8-dihydro configuration. © 1968.

引用

页码：1 / &

共 27 条

[1] UBER PTERINCHEMIE .14. NEUES VERFAHREN ZUR DARSTELLUNG UND STABILISIERUNG VON TETRAHYDROFOLSAURE UND TETRAHYDROPTERINEN [J].