PROGNOSTIC FACTORS IN RECURRENT BREAST-CANCER - RELATIONSHIPS TO SITE OF RECURRENCE, DISEASE-FREE INTERVAL, FEMALE SEX STEROID-RECEPTORS, PLOIDY AND HISTOLOGICAL MALIGNANCY GRADING

被引：64

作者：

BLANCO, G

HOLLI, K

HEIKKINEN, M

KALLIONIEMI, OP

TASKINEN, P

机构：

[1] TAMPERE CENT HOSP, DEPT RADIOTHERAPY, SF-33520 TAMPERE 52, FINLAND

[2] TAMPERE CENT HOSP, DEPT CLIN CHEM, SF-33520 TAMPERE 52, FINLAND

来源：

BRITISH JOURNAL OF CANCER | 1990年 / 62卷 / 01期

关键词：

D O I：

10.1038/bjc.1990.247

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Site of first recurrence, disease-free interval (DFI), female sex steroid receptors, ploidy measurements as well as histological grading have been analysed as potentially valuable predictive factors in 313 cases of recurrent breast cancer. Univariate and multivariate analyses show histological grading, site of recurrence and disease free interval to be useful prognostic variables when assessing prognosis once disease has recurred. High concentrations of oestrogen receptors (ER) were found in patients with bone metastases, whereas lower concentrations of ER were related to visceral recurrences. Ploidy measurements failed in this study to give any predictive information once disease recurred. © The MacMillan Press Ltd., 1990.

引用

页码：142 / 146

页数：5

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