THE INVITRO AND INVIVO ANTI-RETROVIRUS ACTIVITY, AND INTRACELLULAR METABOLISM OF 3'-AZIDO-2',3'-DIDEOXYTHYMIDINE AND 2',3'-DIDEOXYCYTIDINE ARE HIGHLY DEPENDENT ON THE CELL SPECIES

被引：207

作者：

BALZARINI, J ^{[1
]}

PAUWELS, R ^{[1
]}

BABA, M ^{[1
]}

HERDEWIJN, P ^{[1
]}

DECLERCQ, E ^{[1
]}

BRODER, S ^{[1
]}

JOHNS, DG ^{[1
]}

机构：

[1] NCI,DIV CANC TREATMENT,DEV THERAPEUT PROGRAM,BETHESDA,MD 20892

来源：

BIOCHEMICAL PHARMACOLOGY | 1988年 / 37卷 / 05期

关键词：

D O I：

10.1016/0006-2952(88)90178-5

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：897 / 903

页数：7

共 37 条

[1] BOTH 2',3'-DIDEOXYTHYMIDINE AND ITS 2',3'-UNSATURATED DERIVATIVE (2',3'-DI-DEOXYTHYMIDINENE) ARE POTENT AND SELECTIVE INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS-REPLICATION INVITRO [J].

BABA, M ;

PAUWELS, R ;

HERDEWIJN, P ;

DECLERCQ, E ;

DESMYTER, J ;

VANDEPUTTE, M .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1987, 142 (01) :128-134

[2] STRATEGIES FOR THE MEASUREMENT OF THE INHIBITORY EFFECTS OF THYMIDINE ANALOGS ON THE ACTIVITY OF THYMIDYLATE SYNTHASE IN INTACT MURINE LEUKEMIA L1210-CELLS [J].

BALZARINI, J ;

DECLERCQ, E .

BIOCHIMICA ET BIOPHYSICA ACTA, 1984, 785 (1-2) :36-45

[3] ROLE OF THYMIDINE KINASE IN THE INHIBITORY ACTIVITY OF 5-SUBSTITUTED-2'-DEOXYURIDINES ON THE GROWTH OF HUMAN AND MURINE TUMOR-CELL LINES [J].

BALZARINI, J ;

DECLERCQ, E ;

TORRENCE, PF ;

MERTES, MP ;

PARK, JS ;

SCHMIDT, CL ;

SHUGAR, D ;

BARR, PJ ;

JONES, AS ;

VERHELST, G ;

WALKER, RT .

BIOCHEMICAL PHARMACOLOGY, 1982, 31 (06) :1089-1095

[4] POTENT AND SELECTIVE ANTI-HTLV-III/LAV ACTIVITY OF 2',3'-DIDEOXYCYTIDINENE, THE 2',3'-UNSATURATED DERIVATIVE OF 2',3'-DIDEOXYCYTIDINE [J].

BALZARINI, J ;

PAUWELS, R ;

HERDEWIJN, P ;

DECLERCQ, E ;

COONEY, DA ;

KANG, GJ ;

DALAL, M ;

JOHNS, DG ;

BRODER, S .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1986, 140 (02) :735-742

[5]

BALZARINI J, 1983, MOL PHARMACOL, V23, P175

[6]

BALZARINI J, IN PRESS CLIN USE AN

[7]

BALZARINI J, IN PRESS MOL PHARM

[8] ISOLATION OF A T-LYMPHOTROPIC RETROVIRUS FROM A PATIENT AT RISK FOR ACQUIRED IMMUNE-DEFICIENCY SYNDROME (AIDS) [J].

BARRESINOUSSI, F ;

CHERMANN, JC ;

REY, F ;

NUGEYRE, MT ;

CHAMARET, S ;

GRUEST, J ;

DAUGUET, C ;

AXLERBLIN, C ;

VEZINETBRUN, F ;

ROUZIOUX, C ;

ROZENBAUM, W ;

MONTAGNIER, L .

SCIENCE, 1983, 220 (4599) :868-871

[9]

BJURSELL G, 1973, J BIOL CHEM, V248, P3904

[10] A PATHOGENIC RETROVIRUS (HTLV-III) LINKED TO AIDS [J].

BRODER, S ;

GALLO, RC .

NEW ENGLAND JOURNAL OF MEDICINE, 1984, 311 (20) :1292-1297

← 1 2 3 4 →