EFFECT OF SOME QUATERNARY AMMONIUM COMPOUNDS AND LOCAL ANAESTHETICS ON ELECTROGENIC COMPONENT OF SODIUM PUMP IN MAMMALIAN NON-MYELINATED NERVE FIBRES

被引：13

作者：

DENHERTOG, A

RITCHIE, JM

机构：

[1] Departments of Pharmacology, Albert Einstein College of Medicine, NY

[2] Yale University School of Medicine, New Haven, CT

来源：

EUROPEAN JOURNAL OF PHARMACOLOGY | 1969年 / 6卷 / 02期

关键词：

C fibres Local anaesthetics; Electrogenic sodium pump; Quaternary ammonium compounds;

D O I：

10.1016/0014-2999(69)90210-6

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

A study has been made of the effect of some quaternary ammonium compounds and of local anaesthetics on the electrogenic component of the sodium pump in non-myelinated fibres of the desheathed rabbit vagus nerve. Neither group of compounds was found to affect this metabolic response. © 1969.

引用

收藏

页码：138 / +

页数：1

相关论文

共 12 条

[1] THE ACTION OF ACETYLCHOLINE ON CONDUCTION IN MAMMALIAN NON-MYELINATED FIBRES AND ITS PREVENTION BY AN ANTICHOLINESTERASE [J].

ARMETT, CJ ;

RITCHIE, JM .

JOURNAL OF PHYSIOLOGY-LONDON, 1960, 152 (01) :141-158

[2] ACTION OF ACETYLCHOLINE AND SOME RELATED SUBSTANCES ON CONDUCTION IN MAMMALIAN NON-MYELINATED NERVE FIBRES [J].

ARMETT, CJ ;

RITCHIE, JM .

JOURNAL OF PHYSIOLOGY-LONDON, 1961, 155 (02) :372-&

[3] COMPETITIVE ACTION OF CALCIUM AND PROCAINE ON LOBSTER AXON - A STUDY OF MECHANISM OF ACTION OF CERTAIN LOCAL ANESTHETICS [J].

BLAUSTEIN, MP ;

GOLDMAN, DE .

JOURNAL OF GENERAL PHYSIOLOGY, 1966, 49 (05) :1043-+

[4]

BUNKER JP, 1965, PHARMACOL REV, V17, P183

[5]

DENHERTOG A, IN PRESS

[6] COMMON MODE OF ACTION OF 3 AGENTS THAT DECREASE TRANSIENT CHANGE IN SODIUM PERMEABILITY IN NERVES [J].

HILLE, B .

NATURE, 1966, 210 (5042) :1220-&

[7] ORIGIN OF INITIAL HEAT ASSOCIATED WITH A SINGLE IMPULSE IN MAMMALIAN NON-MYELINATED NERVE FIBRES [J].

HOWARTH, JV ;

KEYNES, RD ;

RITCHIE, JM .

JOURNAL OF PHYSIOLOGY-LONDON, 1968, 194 (03) :745-&

[8]

NACHMANSOHN D, 1959, CHEMICAL MOLECULAR B

[9] ON ELECTROGENIC SODIUM PUMP IN MAMMALIAN NON-MYELINATED NERVE FIBRES AND ITS ACTIVATION BY VARIOUS EXTERNAL CATIONS [J].

RANG, HP ;

RITCHIE, JM .

JOURNAL OF PHYSIOLOGY-LONDON, 1968, 196 (01) :183-&

[10] A NEW METHOD FOR MEASURING MEMBRANE POTENTIALS WITH EXTERNAL ELECTRODES [J].

STAMPFLI, R .

EXPERIENTIA, 1954, 10 (12) :508-509